Category Archives: Drugs

Amphotericin B Desoxycholate, Amphotericin B Lipid-Based (Abelcet, Fungizone)

Antifungal Highlights Of Prescribing Information • Systemic antifungal used for serious mycotic infections • Must be administered IV • Nephrotoxicity is biggest concern, particularly with the deoxycholate form; newer lipid based products are less nephrotoxic & penetrate into tissues better, but are more expensive • Renal function monitoring essential • Amphotericin B Desoxycholate, Amphotericin B… Read More »

Amoxicillin / Clavulanate Potassium, Amoxicillin / Clavulanic Acid (Clavamox, Augmentin)

Potentiated Aminopenicillin Highlights Of Prescribing Information • Bactericidal aminopenicillin with beta-lactamase inhibitor that expands its spectrum. Not effective against Pseudomonas or Enterobacter • Most likely adverse effects are GI related, but hypersensitivity & other adverse effects rarely occur What Is Amoxicillin / Clavulanate Potassium, Amoxicillin / Clavulanic Acid Used For? Amoxicillin/potassium clavulanate tablets and oral… Read More »

Amoxicillin (Amoxil, Amoxi-Tabs)

Aminopenicillin Highlights Of Prescribing Information • Bactericidal aminopenicillin with same spectrum as ampicillin (ineffective against bacteria that produce beta-lactamase) • Most likely adverse effects are GI-related, but hypersensitivity & other adverse effects rarely occur • Available in oral & parenteral dosage forms in USA What Is Amoxicillin Used For? The aminopenicillins have been used for… Read More »

Ammonium Molybdate, Ammonium Tetrathiomolybdate (Molypen)

Copper Poisoning Treatment Highlights Of Prescribing Information • Used primarily to treat copper poisoning in food animals (esp. sheep) • Consider contacting FDA for guidance in treating food animals What Is Ammonium Molybdate, Ammonium Tetrathiomolybdate Used For? Ammonium molybdate and ammonium tetrathiomolybdate (TTM) are used for the investigational or compassionate treatment of copper poisoning in… Read More »

Ammonium Chloride (Uroeze)

Acidifying Agent Highlights Of Prescribing Information • Urinary acidifier; treatment of metabolic alkalosis • Contraindicated in patients with hepatic failure or uremia • Potential adverse effects are primarily GI distress; IV use may lead to metabolic acidosis • May increase excretion of quinidine; decrease efficacy of erythromycin or aminoglycosides in urine What Is Ammonium Chloride… Read More »

Amlodipine Besylate (Norvasc)

Calcium Channel Blocker Highlights Of Prescribing Information • Calcium channel blocker used most often for treating hypertension, especially in cats • Slight negative inotrope; use with caution in patients with heart disease, hepatic dysfunction • Potentially may cause anorexia & hypotension in cats early in therapy • Hypertension may rapidly reoccur if dosages are missed… Read More »

Amitriptyline HCL (Elavil)

Tricyclic Behavior Modifier; Anti-Pruritic; Neuropathic Pain Modifier Highlights Of Prescribing Information • Tricyclic “antidepressant” used primarily for behavior disorders & neuropathic pain/pruritus in small animals • May reduce seizure thresholds in epileptic animals • Sedation & anticholinergic effects most likely adverse effects • Overdoses can be very serious in both animals & humans What Is… Read More »

Amiodarone HCL (Cordarone, Pacerone)

Class III Antiarrhythmic Highlights Of Prescribing Information • Antidysrhythmic agent that can be used in dogs for arrhythmias associated with left ventricular dysfunction or to convert atrial fib into sinus rhythm; very limited experience warrants cautious use • May be useful in horses to convert atrial fib or V tach into sinus rhythm • Contraindicated… Read More »

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Aminopentamide Hydrogen Sulfate (Centrine)

Anticholinergic/Antispasmodic Highlights Of Prescribing Information • Anticholinergic/antispasmodicfor GI indications in small animals • Typical adverse effect profile (“dry, hot, red”); potentially could cause tachycardia • Contraindicated in glaucoma; relatively contraindicated in tachycardias, heart disease, GI obstruction, etc. What Is Aminopentamide Hydrogen Sulfate Used For? The manufacturer states that the drug is indicated “in the treatment… Read More »