Name of Drug | Dose | Route |
Acepromazine | 0.03-0.066 mg/kg for sedation | IM |
0.033-0.055 mg/kg followed by 0.055-0.066 mg/kg butorphanol | IV | |
0.04 mg/kg followed by 0.6 mg/kg meperidine | IV | |
0.02-0.055 mg/kg q8h for α-adrenoceptor blockade | IM | |
Acetazolamide | 2.2 mg/kg q12h-q6h | PO |
Acetylcysteine (10%) | 2-5 ml/50 kg q6h | Aerosol |
10% topical solution q1-4h | Ophthalmic | |
Aclometasone | 0.05% | Topical |
Acyclovir | 5-10 mg/kg q8h | PO |
Acyclovir 3% | q3-4h | Ophthalmic |
Adrenocorticotrophic hormone | 0.26 mg q8-12h (depot preparation) | IM |
0.125 mg/foal (tests adrenal function of premature foals) | IV | |
Albendazole | 25 mg/kg q12h for 5 days for Dictyocaulus arnfieldi | PO |
50 mg/kg q12h for 2 days for Strongylus vulvaris larvae | PO | |
4-8 mg/kg q12h for 1 month for Echinococcus | PO | |
Albuterol | 1-2 μg/kg | Inhalation |
Alfaprostol | 3 mg/450 kg for luteolysis; 2 doses 14-18 days apart | IM |
Allopurinol | 5 mg/kg | IV |
alpha-tocopherol | 1.5-4.4 mg/kg q24h | PO |
Altrenogest | 0.044 mg/kg q24h for 8-12 days; for estrus synchronization follow with luteolytic dose of prostaglandin F2α | PO |
0.044 mg/kg to prevent aggression | PO | |
0.44 mg/kg q24h for pregnancy maintenance | PO | |
Aluminum hydroxide | 200-250 ml q8h (antacid) | PO |
60 mg/kg | PO | |
Amikacin | 3.5-7.5 mg/kg q12h to q6h | IM or SQ |
15-20 mg/kg q24h | IM or SQ | |
1-10 mg/kg q12h for foals | Slow IV or IM | |
75-100 mg | Subconjunctival | |
125-250 mg | Intraartricular | |
2 g buffered with equal volume of 75% sodium bicarbonate | Intrauterine | |
15 mg/ml; combine 250 mg amikacin with 15 ml artificial tears | Ophthalmic | |
Aminocaproic acid | 20 mg/kg diluted 1:9 in saline and administered over 30-60 min | IV |
Aminophylline | 5-10 mg/kg q12h | PO |
Aminopropazine fumarate | 0.5 mg/kg q12h | IM or IV |
Aminopyrine | 2.5-10 mg/450 kg | IV or IM |
Ammonium chloride | 20-520 mg/kg q24h (acidifier) | PO |
Amoxicillin | 10-22 mg/kg q8h | IM |
Amoxicillin trihydrate | 6-10 mg/kg q12h-q8h | IM |
Amphotericin B | 0.05 mg/kg q2d for 1 month
Introduce over 5 days; dissolve in 1 L 5% dextrose and administer over 1 hour via large-bore catheter |
IV |
0.15% solution in 5% glucose topically 4-6 times daily | Ophthalmic | |
Ampicillin Na | 10-15 mg/kg q8h-q6h | IV or IM |
Ampicillin Na trihydrate | 11-22mg/kg q12h or q8h | IM or PO |
50 mg | Subconjunctival | |
50 mg/ml; reconstitute 1 g with 5 ml water and add 15 ml artificial tears | Ophthalmic | |
Antidiuretic hormone | 60 IU q6h for diabetes insipidus | IV |
Ascorbic acid | 30mg/kg q12h in IV fluids | IV |
Aspirin | 10-100 mg/kg q12h | PO |
Atipamezole | 0.05-1.0 mg/kg | IV |
Atracurium | 0.04-0.07 mg/kg | IV |
Atropine | 0.01-0.1 mg/kg | IV, IM, or SQ |
Atropine HCl | 0.5%-1.0% q6-48h | Ophthalmic |
Aurothioglucose | 1 mg/kg | IM |
Azathioprine | 2-5 mg/kg q24h loading dose, then q48h for maintenance | PO |
Azithromycin | 10 mg/kg q24h for 5 days followed by q48h | PO |
Azlocillin | 25-75 mg/kg q6h | IV |
Beclamethasone | 3.75mg q12h | Inhalation |
Benztropine mesylate | 8 mg | Slow IV drip |
Betamethasone | 0.02-0.1 mg/kg | IM or PO |
4-10 mg | Intralesional | |
Bethanecol | 0.025-0.1 mg/kg q8h or q6h | SQ |
0.3-0.4 mg/kg q8h or q6h | PO | |
Bismuth subsalicylate | 0.5-1 ml/kg q4-6h in foals | PO |
1-2L/450 kg q12h | PO | |
Boldenone undecylenate | 1 mg/kg repeated at 3-week intervals | IM |
Botulinum antitoxin | 100-150 IU/ml: 200 ml/foal or 500 ml/adult | IV or IM |
Bretylium tosylate | 3-10 mg/kg | IV |
Buparavaquone | 4-6 mg/kg, single dose | IV |
Butorphanol tartrate | 0.01-2 mg/kg, see xylazine, detomidine, and acepromazine | IV or IM |
Caffeine | 10 mg/kg loading dose, then 2.5-3 mg/kg q24h | PO |
Calcium chloride | 1-2 g/450 kg, slowly to effect | IV |
Calcium gluconate | 0.5 ml/kg of 10% solution | Slow IV |
Cambendazole | 20 mg/kg for Strongyloides westeri | PO |
Captan | 3% solution | Topical |
Carbenicillin Na indanyl | 50-80 mg/kg q12h or q8h | IV or IM |
200 mg | Subconjunctival | |
6g | Intrauterine | |
Carbon disulfide | 24 mg/450 kg | PO |
Carprofen | 0.7 mg/kg q24h | IV |
Casein (iodinated) | 5 g q24h | PO |
Cefaclor | 20-40 mg/kg q8h | PO |
Cefadroxil | 22 mg/kg q12h | PO |
25 mg/kg q4-6h for foals | IV | |
Cefamandole | 10-30 mg/kg q4-8h | IV or IM |
Cefazolin Na | 15 mg/kg q12h or q8h | IV or IM |
50 mg | Subconjunctival | |
50 mg/ml; reconstitute 1 gm with 5 ml water and add 15 ml artificial tears | Ophthalmic | |
Cefepime | 6 mg/kg q8h for adults | IV |
11 mg/kg q8h for foals | IV | |
Cefixime | 400 mg/kg q8h | PO |
Cefonicid | 10-15 mg/kg q24h | IV or IM |
Cefoperazone | 30-50 mg/kg q12h or q8h | IV or IM |
Ceforanide | 5-10 mg/kg q12h | IV or IM |
Cefotaxime Na | 15-25 mg/kg q12h-q8h | IV or IM |
Cefotetan | 15-30 mg/kg q12h | IV or IM |
Cefoxitin | 30-40 mg/kg q8h or q6h | IM |
20 mg/kg q6h | IV | |
Ceftazidime | 25-50 mg/kg q12h | IV or IM |
Ceftiofur | 1-5 mg/kg q24h-q12h | IV or IM |
1 g | Intrauterine | |
Ceftizoxime | 25-50 mg/kg q12h or q8h | IV or IM |
Ceftriaxone | 25-50 mg/kg q12h | IV or IM |
Cefuroxime | 25-50 mg/kg q8h | IV or IM |
Cefuroxime axetil | 250-500 mg/kg q12h | PO |
Cephalexin | 10-30 mg/kg q8h-q6h | PO |
Cephalothin Na | 20-40 mg/kg q8h-q6h | IV or IM |
100mg | Subconjunctival | |
50 mg/ml; reconstitute 1 gm with 5 ml water and add 15 ml artificial tears | Ophthalmic | |
Cephapirin | 30 mg/kg q4-6h | IV or IM |
Cetizoxime Na | 20-30 mg/kg q8h | IV |
Charcoal (activated) | 1-3 g/kg as slurry (1 g in 5 ml water); repeat if necessary in 8-12 hours | PO |
Chloral hydrate | 60-200 mg/kg for foal restraint | IV |
40-100 mg/kg | PO | |
Chloramphenicol palmitate | 4-10 mg/kg q8h or q6h (foal) | PO |
25-50 mg/kg q8h or q6h (adult) | PO | |
Chloramphenicol succinate | 25 mg/kg q8h-q6h | IV or IM |
50-100 mg | Subconjunctival | |
Chlorhexidine | 0.5%-2% | Topical |
Chlorpromazine | 1 mg/kg | IM |
Cimetidine | 6.6 mg/kg q4-6h | IV |
18 mg/kg q8h | PO | |
2.5-4 mg/kg q8h for 2 months for tumor reduction | PO | |
Cisapride | 0.1 mg/kg | IM |
0.5-0.8 mg/kg q8h for 7 days | PO | |
Clarithromycin | 7.5 mg/kg q12h | PO |
Clenbuterol | 0.8-3.2 μg/kg q12h | PO |
0.8 μg/kg q12h | IV | |
200 μg for uterine relaxation | IM or slow IV | |
Cloprostenol Na | 250-500 μg/450 kg; can repeat in 30 min to 2 hours for parturition induction | IM |
Clotrimazole | 500 mg suspension or cream q24h for 1 week | Intrauterine |
Cloxacillin | 10-30 mg/kg q6h | IM |
Cocaine chloride | 1-1.5 ml of 10 mg/ml | Subconjunctival |
Colistin | 2500 IU/kg q6h | Slow IV |
Corticotropin | 1 IU/kg | IM |
Coumaphos | 0.06% wash, 0.1% dust | Topical |
Cromolyn sodium | 80-300 mg | Inhalation |
Cyclophosphamide | 200-300 mg/m2 q2-3wk | IV |
Cyclosporin A | 0.2%-2.0% topical q6-12h | Ophthalmic |
Cyproheptadine | 0.5 mg/kg q12h | PO |
Cytosine arabinoside | 200-300 mg/m2 q1-2 wk with chlorambucil or cyclophosphamide | IM or SQ |
D-penicillamine | 3-4 mg/kg q6h for 10 days | PO |
Danthron | 15-30 ml/kg | PO |
Dantrolene Na | 10 mg/kg loading dose; then 2.5 mg/kg q2h, maintenance | PO |
2-2.5 mg/kg in saline for acute myopathy | Slow IV | |
1-2 mg/kg q24h to prevent myositis | PO | |
Dembrexine | 0.3-0.5 mg/kg | PO |
Demecarium bromide | 0.25% q12h | Ophthalmic |
Detomidine | 0.005-0.02 mg/kg | IV |
0.01-0.02 mg/kg followed by 0.044-0.066 mg/kg butorphanol | IV | |
0.02-0.04 mg/kg followed by 2.2 mg/kg ketamine | IV | |
Dexamethasone | 0.02-0.2 mg/kg q24h | IV, IM, or PO |
0.5-2 mg/kg for septic shock | IV | |
100 mg/450 kg q24h for 5 days to induce parturition | IV | |
Dexamethasone phosphate | 0.1% q8h | Ophthalmic |
Dexamethasone suspension | 0.1% q3-8h | Ophthalmic |
Dextran (6% solution) | 8 g/kg q24h for up to 3 days | IV |
Diazepam | 0.03-0.5 mg/kg; repeat in 30 minutes if necessary | Slow IV |
Dichlorphenamide | 1 mg/kg q12h | PO |
Dichlorvos | 35 mg/kg | PO |
0.93% solution | Topical | |
Dicloxacillin | 10 mg/kg q6h | IM |
Diethylcarbamazine | 1 mg/kg q24h for 21 days for onchocerciasis | PO |
50 mg/kg q24h for 10 days for verminous myelitis | PO | |
Digoxin | 0.002 mg/kg q12h | IV |
0.01 mg/kg q12h | PO | |
Dihydrostreptomycin | 11 mg/kg q12h | IM or SQ |
Dimercaprol | 2.5-5 mg/kg as 10% solution in oil q4h for 2 days, then q12h until recovery | IM |
Dimethyl glycine | 1-1.6 mg/kg q24h | PO |
Dimethyl sulfoxide (DMSO) | 0.5 mg/kg to 1.0 g/kg (10% solution in 5% dextrose); repeat lower doses q6-12h | IV |
50% solution | Topical | |
Dinoprost tromethamine | 10 mg/450 kg | IM |
Dioctyl sodium sulfosuccinate | 10-20 mg/kg in 4-8 L water q48h | PO |
Dioctyl sodium sulfosuccinate 5% solution | 10 ml in warm water as enema for retained meconium | |
Dioxathion | 0.15% wash | Topical |
Diphenylhydantoin | 1-10 mg/kg q2-4h | IV, IM, or PO |
Dipyrone | 5-22 mg/kg | IV or IM |
Dobutamine | 1-10 μg/kg per minute (250 mg in 500 ml saline infused at 0.45 ml/kg per hour) | IV |
Dolophine HCl | 0.2-0.4 mg/kg | IM |
Domperidone | 0.2 mg/kg | IV |
1.1 mg/kg q24h | PO | |
Dopamine | 1-5 μg/kg per minute (200 mg in 500 ml saline infused at 0.45 ml/kg per hour) | IV |
Doxapram | 0.5-1.0 mg/kg q5min (do not exceed 2 mg/kg in foals) | IV |
0.02-0.05 mg/kg per minute up to 400 mg total for neonatal foal resuscitation | IV | |
Doxepin hydrochloride | 0.5-0.75 mg/kg q12h | PO |
Doxycycline | 3 mg/kg q12h | PO |
0.3% topically q3-6h | Ophthalmic | |
Ecothiophate iodide | 0.03% q12h | Ophthalmic |
EDTA calcium disodium | 75 mg/kg per day in divided doses for lead poisoning | Slow IV |
6.6% solution (1 ml/0.9 kg), q8-12h | IV | |
Eltenac | 0.5 mg/kg | IV |
Enalopril | 0.5 mg/kg q12-24h | PO |
Enrofloxacin | 2.5 mg/kg q12h | PO |
Ephedrine sulphate | 0.7 mg/kg q12h | PO |
Epinephrine | 1-1.5 ml of 0.33 ng/ml | Subconjunctival |
0.01-0.02 mg/foal (foal resuscitation) | IV | |
0.1-0.2 mg/foal (foal resuscitation) | Intratracheal | |
Erythromycin base | 0.1 mg/kg per hour to enhance gut motility | IV |
Erythromycin estolate or ethylsuccinate | 25 mg/kg q12h | PO |
Erythromycin lactobionate | 2.5-5 mg/kg q8h or q6h | IV |
20-40 mg | Subconjunctival | |
Erythromycin phosphate or stearate | 37.5 mg/kg q12h | PO |
Estradiol | 0.004-0.008 mg/kg q2d for urinary incontinence | IM |
Estrone sulfate | 0.04 mg/kg q24h | IM |
Ethyl alcohol (50%) | 5-10 ml/50 kg | Aerosol |
Ethylene diamine dihydriodide | 0.5-1.5 g/450 kg q24h | PO |
Ethylenediaminetetraacetic acid (EDTA) | 0.5% topical solution q2-4h | Ophthalmic |
Etodolac | 10-15 mg/kg q24h | IV or PO |
Famotidine | 3.3 mg/kg q8h | PO |
Febantel | 6 mg/kg | PO |
Fenbendazole | 5 mg/kg | PO |
10 mg/kg for Parascaris equorum | PO | |
50 mg/kg q24h for 3 days for verminous arteritis | PO | |
50 mg/kg for Strongyloides westeri | PO | |
50 mg/kg q24h for 5 days for onchocerca | PO | |
Fenoterol | 2-4 μg/kg | Inhalation |
Fenoprostalene | 0.5 mg/450 kg | SQ |
Fentanyl | Two 10 mg patches | |
Ferrous sulfate | 2 mg/kg q24h | PO |
Florfenicol | Do not administer to horses until more data are available | |
Floxacillin | 10 mg/kg q6h | IM |
Fluconazole | 4 mg/kg q24h | PO |
Flumazenil | 0.5-2.0 mg | Slow IV |
Flumethasone | 0.002-0.008 mg/kg | PO |
Flunixin meglumine | 0.25-1.1 mg/kg q24h-q8h | PO, IM, or IV |
Fluoroprednisolone acetate | 5-20 mg/450 kg | IM |
Fluphenazine | 25 mg/pony (at 320 days gestation for prevention of fescue toxicosis) | IM |
Fluprostenol | 250 μg/450 kg | IM |
Flurbiprofen Na 0.03% | q8h or q6h | Ophthalmic |
Fluticasone propionate | 2000 μg/450 kg | Inhalation |
Folic acid | 40-75 mg | IM |
Folinic acid | 50-100 mg | IM |
Follicle stimulating hormone | 10-50 mg/450 kg | IV, IM, or SQ |
Furazolidone | 4 mg/kg q8h | PO |
Furosemide | 1-3 mg/kg q12h | IV or IM |
250-500 mg 1-4 hours prerace | IV or IM | |
Gentamicin sulfate | 2-4 mg/kg q12h-q6h | IV, IM, or SQ |
6.6-8.8 mg/kg q24h | IV, IM, or SQ | |
10-40 mg | Subconjunctival | |
150 mg (unbuffered) | Intraarticular | |
1-2 g buffered in equal volume of 75% sodium bicarbonate | Intrauterine | |
6 mg/ml; combine 100 mg with 15 ml artificial tears | Ophthalmic | |
Clucagon | 25-50 mg/kg | IV |
Glycerin | 1 g/kg | PO |
Glycerol | 0.5-2 g/kg for brain edema | IV |
Glycerol (5%) | 2-5 ml/50 kg | Aerosol |
Glycerol guaiacolate | 110 mg/kg for convulsions | IV |
0.1-0.2 g/50 kg q6h expectorant | PO | |
Glycopyrolate | 0.005-0.01 mg/kg | IV |
Glycosaminoglycan polysulfated | 250 mg once weekly | Intraarticular |
1 mg/kg q5days | IM | |
Gonadotropin-releasing hormone | 0.05 mg 2 and 0.5 hours prebreeding for low libido | SQ |
0.04 mg 6 hours prebreeding to induce ovulation | IM | |
Griseofulvin | 10 g/450 kg q24h for 2 weeks, then 5 g q24h for 7 weeks | PO |
Guaifenesin (5%-10%) | To effect (— 50-110 mg/kg needed for induction) | Slow IV |
5% with 4.4 mg/kg thiamylal | Rapid IV | |
Heparin | 10 IU/kg loading dose | IV |
15 IU/kg per hour maintenance | Slow IV | |
40-100 IU/kg q12h or q6h for acute laminitis | IV | |
20-90 IU/kg for peritonitis prevention | SQ | |
Heparin calcium | 150 IU/kg loading dose, then 125 IU/kg q12h for 6 doses, then 100 IU/kg | SQ |
Heparin sodium | 40-80 IU/kg | IV |
2 hours later, 40 IU/kg, then 40 IU/kg q12h | SQ | |
Heparin (low-molecular-weight) | 50 IU/kg q12h | SQ |
Hetastarch | 5-10 ml/kg/day | IV |
Human chorionic gonadotrophin | 2000 IU to synchronize ovulation | IV |
Hyaluronate Na | 10-50 mg/joint (see manufacturer’s recommendations) | Intraarticular |
500 mg q4d for 7 doses | IM | |
Hyaluronic acid | 20-120 mg locally around inflamed tendon | |
20-50 mg | Intraarticular | |
Hydralazine | 0.5 mg/kg | IV |
Hydrochlorothiazide | 250 mg/450 kg q24h | PO |
Hydrocortisone sodium succinate | 1-4 mg/kg | IV drip |
Hydroxyethyl starch | See Hetastarch | |
Hydroxyzine HCl | 0.5-1 mg/kg q12h | IM or PO |
Hyoscine | 0.14 mg/kg | IV |
Idoxuridine 0.1% | q2-6h | Ophthalmic |
Imidocarb diproprionate | 2 mg/kg q24h for 2 days for Babesia caballi | IM |
4 mg/kg q3d for 4 treatments for Babesia equi | IM | |
Imipenem | 15 mg/kg q6-8h for foals | IV |
Imipramine | 100-600 mg q12h for 2 weeks to improve ejaculation | PO |
0.55 mg/kg q8h | IM or IV | |
1.5 mg/kg q8h | PO | |
Insulin | 0.5 IU/kg | IM or SQ |
Insulin — protamine zinc | 0.15 IU/kg q12h | IM or SQ |
Interferon-α 2A (1,000 IU/ml) | 1 ml q24h for 3 weeks, one week off, then repeat | PO |
Iodide Na | 20-40 mg/kg q24h for several weeks | PO |
lodochlorhydroxyquin | 10 g/450 kg (repeat for 3-4 days then gradually reduce dose if response is obtained) | PO |
Ipratropium | 2-3 μg/kg | Inhalation |
Iron cacodylate | 1 g | IV |
Isoflupredone acetate | 10-14 mg | IM |
Isoniazid | 5-20 mg/kg q24h | PO |
Isoproterenol HCl | 0.4 μg/kg by slow infusion (discontinue when heart rate doubles) | IV |
0.05-1 μg/kg per minute for foal resuscitation | IV | |
Isoproterenol (0.05%) | 5-10 ml/50 kg q6h | Aerosol |
Isoxsuprine HCl | 0.4-1.2 mg/kg q12h | IM |
Itraconazole | 3 mg/kg q12h for up to 2 months | PO |
1 % with 30% DMSO topically q4-6h (not for use with subpalpebral lavage system) | Ophthalmic | |
Ivermectin | 0.2 mg/kg | PO |
0.2 mg/kg twice at 4-day intervals for lice and mange | PO | |
Kanamycin | 7.5 mg/kg q8h | IV or IM |
1-2 g | Intrauterine | |
Kaopectate | 2-4 qt/450 kg q12h | PO |
Ketamine | See xylazine and detomidine | |
Ketoconazole | 30 mg/kg q24h or q12h (dissolve in 0.2 N HCl) | PO |
Ketoprofen | 2.2 mg/kg | IV or IM |
L-asparginase | 10,000-40,000 IU/m2 q2-3wk | IM |
Lactase | 6,000-9,000 FCC units q3-6h | PO |
Lactulose | 0.2 ml/kg q12h | PO |
Levallorphan tartrate | 0.02-0.04 mg/kg | IV |
Levamisole | 8-11 mg/kg q24h | PO |
Levothyroxine | 10 mg in 70 ml Karo syrup q24h | PO |
Lidocaine | 0.2-0.5 mg/kg bolus q5min up to 1.5 mg/kg total dose | IV |
1.3 mg/kg bolus over 5 minutes, then 0.05 mg/kg per minute for up to 24 hours for treatment of ileus | IV | |
1-2 mg/kg followed by 20-50 μg/kg/min for ventricular arrythmias in foals | IV | |
Lime sulfur | 3%-5% | Topical |
Lindane | 3% spray | Topical |
Loperamide | 0.1-0.2 mg/kg q6h | PO |
Magnesium hydroxide | 200-250 ml q8h (antacid) | PO |
Magnesium sulfate | 0.2-1 g/kg dissolved in 4 L warm water q24h | PO |
4 mg/kg boluses q2min up to 50 mg/kg total dose | IV | |
Malathion | 0.5% wash, 5% dust | Topical |
Mannitol (20%) | 0.25-2.0 g/kg | Slow IV |
Mebendazole | 8.8 mg/kg | PO |
20 mg/kg q24h for 5 days for Dictyocaulus arnfieldi | PO | |
50 mg/kg q24h for 5 days for onchocerciasis | PO | |
Meclofenamic acid | 2.2 mg/kg q12h | PO |
Megestrol acetate | 65-85 mg/kg q24h | PO |
Meperidine | See acepromazine | |
Metaclopramide HCl | 10 mg/kg | IV |
Methadone | 0.05-0.2 mg/kg | IV |
Methetharimide | 10-20 mg/kg | IV |
Methicillin | 25 mg/kg q4-6h | IM |
100 mg | Subconjunctival | |
Methionine (D-L) | 1 g/kg q24h | PO |
Methocarbamol | 5-55 mg/kg q6h | Slow IV |
40-300 mg/kg for convulsions | Slow IV | |
Methoxychlor | 0.5% wash | Topical |
Methylcellulose flakes | 0.25-0.5 kg/450 kg in 10 L water | PO |
Methylene blue | 8.8 mg/kg as 1 % solution | IV |
Methylprednisolone acetate | 0.2-0.7 mg/kg | IM |
Methylprednisolone sodium succinate | 2-4 mg/kg | IV |
30 mg/kg, then 5.4 mg/kg per hour for 23 hours for CNS trauma | IV | |
20 mg | Subconjunctival | |
Up to 100 mg | Intrabursal or intraarticular | |
Methylsulfonylmethane | 30 g/450 kg q24h | PO |
Methysulfmethoxine | 15-20 mg/kg q24h | PO |
Metoclopramide | 0.25 mg/kg q8h or q6h | IV drip or SQ |
0.6 mg/kg q4h | PO | |
Metronidazole | 15 mg/kg q6h | IV or PO |
Mezlocillin | 25-75 mg/kg q6h | IV |
Miconazole | 2% vaginal cream topically q4-6h (not for use with subpalpebral lavage system) | Ophthalmic |
1 % solution used topically q4-6h | Ophthalmic | |
Midazolam | 0.05-0.2 mg/kg | IV or IM |
Mineral oil | 10 ml/kg q24h | PO |
Minocycline | 3 mg/kg q12h | PO |
Misoprostol | 1-4 μg/kg q24h | PO |
Morphine sulfate | 0.2-0.4 mg/kg | IM |
0.25-0.75 mg/kg | IV | |
Moxalactam | 50 mg/kg q8h | IV or IM |
Moxidectin | 0.4 mg/kg | PO |
Nafcillin | 10 mg/kg q6h | IM |
Naloxone | 0.01-0.02 mg/kg | IV |
Naproxen | 10 mg/kg q24h or q12h | PO or IV |
Natamycin | Topically q4-6h; dilute to 3.33% for use with subpalpebral lavage system | Ophthalmic |
Neomycin | 1 g/horse q6h | PO |
2 g/horse q12h | PO | |
0.5 g/foal q6h | PO | |
1.5g/foalq12h | PO | |
3-4 g | Intrauterine | |
5 mg/kg q8h for 2 days to reduce ammonia production in the bowel | PO | |
Neostigmine | 0.004-0.02 mg/kg | SQ |
Netilmicin | 2mg/kg q12h-q8h | IV or IM |
Niclosamide | 100 mg/kg | PO |
Nitrofurantoin | 3 mg/kg q12h | IM |
Nizatidine | 6.6 mg/kg q8h | PO |
Norepinephrine | 0.01 mg/kg | IM |
Nystatin | 500,000 IU in 30 ml saline q24h for 7-10 days | Intrauterine |
Omeprazole | 1.5 mg/kg q24h | IV |
Ouabain | 2.5-3 mg/450 kg q2h until heart rate slows or intoxication develops; do not exceed 10 g total | IV |
Orbifloxacin | 2.5 mg/kg q24h | PO |
Oxacillin | 25-50 mg/kg q12h or q8h | IV or IM |
Oxfendazole | 10 mg/kg | PO |
Oxibendazole | 10-15 mg/kg | PO |
15 mg/kg for Strongyloides westeri | PO | |
Oxymorphone | 0.02-0.03 mg/kg | IM |
Oxytetracycline | 5-20 mg/kg q24h | IV |
44-70 mg/kg (single dose for tendon contracture in foals) | IV | |
Oxytocin | 2.5-5 IU/450 kg as bolus q20min | IV |
80-100 IU in 500 ml saline | Slow IV | |
10-20 IU/450 kg | IM or IV | |
1-3 IU/450 kg for milk letdown | IV | |
0.5-10 IU/kg to induce parturition | IV | |
Pancuronium | 0.04-0.066 mg/kg | IV |
Paromomycin | 100 mg/kg q24h | PO |
Penicillamine d | 3-4 mg/kg q6h for 10 days | PO |
Penicillin G | ||
Penicillin Na | 10,000-50,000 IU/kg q6h | IV or IM |
Penicillin K | 10,000-50,000 IU/kg q6h | IV or IM |
20,000 IU/kg q6h | PO | |
5 x 106 IU | Intrauterine | |
Penicillin procaine | 20-50,000 IU/kg q12h or q8h | IM |
Penicillin benzathine | 10,000-40,000 IU/kg q48-72h | IM |
Penicillin V | 110,000 mg/kg q12h-q6h | PO |
Pentazocine | 0.8 mg/kg | IV |
Pentobarbital | 2-20 mg/kg for convulsions | IV |
Pentosan sulfate | 250mg q7-10d | Intraarticular |
Pentoxifylline | 8.4 mg/kg q12h | PO |
Pentylenetetrazol | 6-10 mg/kg | IV |
Pergolide mesylate | “High dose” 0.006-0.01 mg/kg q24h | PO |
“Low dose” 0.002 mg/kg q24h | PO | |
Permethrin | 2% | Topical spray |
Perphenazine | 0.3-0.5 mg/kg q12h | PO |
Phenobarbital | 5-25 mg/kg in 30 ml saline for convulsing foals | IV over 30 minutes |
9 mg/kg q8h for maintenance | IV | |
Phenothiazine | 55 mg/kg | PO |
27.5 mg/kg with piperazine | PO | |
Phenoxybenzamine HCl | 0.7-1 mg/kg in 500 ml saline q8h or q6h | IV |
Phenylbutazone | 2-4.4 mg/kg q12h | PO or IV |
Phenylephrine | 10% | Ophthalmic |
0.1-0.2 μg/kg/min; total dose not to exceed 0.01 mg/kg | IV | |
Phenytoin | 5-10 mg/kg for convulsing foals | IV |
1-5 mg/kg for maintenance q4h | IV, IM, or PO | |
10-22 mg/kg q12h for digoxin-induced arrhythmias | PO | |
Physostigmine | 0.1-0.6 mg/kg | IM or slow IV |
Pilocarpine HCl | 4% gel q12h-q6h | Ophthalmic |
Piperazine | 88-110 mg/kg | PO |
Pipercillin | 15-50 mg/kg q12h-q6h | IV or IM |
Pirbuterol | 1-2 μg/kg | Inhalation |
Polymixin B or E | 5000-10,000 IU/kg q6h | PO |
1 x 106 IU | Intrauterine | |
Ponazuril | 5 mg/kg q24h for 28 days | PO |
Potassium chloride | 40 g in 4-6 L water q12h | PO |
20-40 mEq/L of fluid | IV | |
Potassium iodide | 2-20 g q24h | PO |
Potassium permanganate | 1 % solution for mouthwash | |
Povidone iodine | 5% solution topically q24h (irritating to conjunctiva) | Ophthalmic |
Pralidoxime chloride | 20-50 mg/kg | Slow IV or IM |
Praziquantel | 0.5-1.0 mg/kg for tapeworms | PO |
Prednisolone acetate | 1% topical q1-6h | Ophthalmic |
Prednisolone | 0.2-4.4 mg/kg q24h or q12h | PO or IM |
Na succinate | 2-5 mg/kg for septic shock | IV |
Primidone | 1-2g/foal q12h-q6h | PO |
Procainamide | 35 mg/kg | PO |
Progesterone | 150 mg q24h to suppress estrus | IM |
300 mg q24h to maintain pregnancy | IM | |
Progesterone repositol | 1000 mg/450 kg once weekly for abortion prevention | IM |
Promazine | 0.25-1 mg/kg | IV |
1-2 mg/kg granules | PO | |
Propafenone | 0.5-1.0 mg/kg | IV |
Propantheline bromide | 0.014 mg/kg | IV |
Proparacaine | 0.5% | Ophthalmic |
Propofol | 2.4 mg/kg for anesthesia induction in foals, then 0.3 mg/kg per minute for maintenance | IV |
Propranolol | 0.38-0,78 mg/kg q8h | PO |
0.05-0.16 mg/kg q12h | IV | |
Prostaglandin-E2 analogues | 1-4 μg/kg q24h for gastric protection | PO |
Prostaglandin F2α | 10mg | IM |
Prostalene | 2 mg/450 kg, 2 doses 2 weeks apart | SQ |
Psyllium mucilloid | 1 g/kg q24h-q6h | PO |
Pyrantel embonate | 38 mg/kg for tapeworms | PO |
Pyrantel tartrate | 2.64 mg/kg q24h for control of intestinal nematodes | PO |
Pyrantel pamoate | 6.6 mg/kg | PO |
13.2 mg/kg for tapeworms | PO | |
Pyrilamine maleate | 1 mg/kg | IV, IM, or SQ |
Pyrimethamine | 0.25 mg/kg q12h for 3 days then q24h for 27 days (for equine protozoal myeloencephalitis) | PO |
Quinidine sulfate | 22 mg/kg q2-6h | PO |
Quinidine gluconate | 2.2 mg/kg q10min until 8-10 mg/kg total | IV |
0.7-3 mg/kg per hour | IV | |
Ranitidine | 6.6 mg/kg q8h | PO |
1.5 mg/kg q8h | IV | |
Reserpine | 2-5 mg/kg q24h | PO |
Rifampin | 10-20 mg/kg q24h | PO |
3-5 mg/kg q12h with erythromycin for Rhodococcus equi | PO | |
Romifidine | 0.08-1.0 mg/kg | IV |
Ronnel | 2.5% spray | Topical |
Saline (hypertonic) | 7.5%, 4 ml/kg for hypovolemia | IV over 20 minutes |
Selenium (Na selenite) | 5.5 mg/450 kg | IM |
Silver sulfadiazine | 1% cream topically q4-6h (not for use with subpalpebral lavage system) | Ophthalmic |
Sodium bicarbonate | 30-150g/day | PO |
Sodium hypochlorite | 0.5% | Topical |
Sodium iodide | 20-40 mg/kg q24h | PO |
Sodium sulfate | Up to 3 g/kg dissolved in warm water | PO |
Sodium thiosulfate (20%) | 0.22 ml/kg | Slow IV |
Spectinomycin | 20 mg/kg q8h | IM |
Stanozolol | 0.5 mg/kg, up to 4 doses q1-2 wk | IM |
Stilbestrol | 30 mg/450 kg | IM |
Stirofos | 1 % wash | Topical |
Streptomycin | 11 mg/kg q12h | IM or SQ |
Succinylcholine | 330 mg/kg | IV or IM |
Sucralfate | 1-4g q12h-q6h | PO |
Sulfonamides | 100-200 mg/kg on day 1, then | IV, IM, or SQ |
50-100 mg/kg subsequently (check labels on each product) | ||
Sulfonamides, potentiated | 30 mg/kg q12h or q8h | PO |
Sulpiride | 3.3 mg/kg q24h | PO |
Suprofen 1% | q12h-q8h | Ophthalmic |
Telazol | 1-2 mg/kg for anesthesia induction | IV |
Terbutaline | 0.02-0.06 mg/kg q12h | IV, PO, or inhalation |
Testosterone (aqueous) | 0.1-0.2 mg/kg q48h for 2 weeks for inadequate libido | SQ |
Tetanus antitoxin | 100 IU/kg q3-5days for treatment of tetanus | IM, SQ, or IV |
Tetracycline | 6.6-11 mg/kg q12h | IV |
Tetramethrin | 0.4% solution, wipe-on | Topical |
Theophylline | 1 mg/kg q6h | PO |
Thiabendazole | 44 mg/kg | PO |
88 mg/kg for Parascaris equorum | PO | |
440 mg/kg q24h for 2 days for verminous arteritis | PO | |
4% solution in saline or 90% DMSO | Topical | |
Thiamine HCl | 0.5-5 mg/kg | IM |
Thiamylal Na | 2-4 mg/kg | IV |
Thiopental | 4-10 mg/kg as 10% solution | IV |
Thyroxine l | 0.01 mg/kg q24h | PO |
Ticarcillin | 40-80 mg/kg q8h | IV or IM |
6g | Intrauterine | |
Ticarcillin clavulanate | 50 mg/kg q8h-q6h | IV |
Ticarcillin/clavulanic acid | 6 g/200 mg | Intrauterine |
Tilmicosin | Do not administer to horses until more data are available. | |
Timolol maleate | 0.5% q12h | Ophthalmic |
Tobramycin | 1-1.7 mg/kg q8h (human dose) | IV or IM |
10-30 mg | Subconjunctival | |
6 mg/ml; combine 100 mg with 15 ml artificial tears | Ophthalmic | |
Tocopherol acetate | 6000 IU/250-500 kg q24h | PO |
Tolazoline | 0.5 mg/kg | IV |
Toxaphene | 0.5% wash | Topical |
Tranexamic acid | 1 g | IV |
Triamcinolone | 0.02-0.1 mg/kg | IM |
1-3 mg/site up to 18 mg total | Intralesional | |
1-2mg | Subconjunctival | |
Trichlorfon | 40 mg/kg | PO |
Trichlormethiazide | 200 mg/450 kg | PO |
Trifluorothymidine 1% | q1-2h | Ophthalmic |
Triflupromazine | 0.2-2.0 mg/kg | IV |
Trifluridine 1 % | q2-6h | Ophthalmic |
Trimethoprim-sulfadiazine | 15 mg/kg q12h | IV |
15-30 mg/kg q12h | PO | |
2.5-5 g q24h | Intrauterine | |
Tripelennamine HCl | 1 mg/kg | IV or IM |
Tromethamine | 300 mg/kg | IV |
Tropicamide | 0.5%-1% | Ophthalmic |
Tylosin | 10 mg/kg q12h | IM |
Vancomycin | 20-40 mg/kg q12h-q6h | IV or PO |
Vedaprofen | 2.2 mg/kg q12h | IV |
Verapamil | 0.025-0.5 mg/kg q30min | IV |
Vidarabine | 3% ointment at least q6h | Ophthalmic |
Vincristine | 0.01-0.025 mg/kg q7d | IV |
Vinegar | 250 ml/450 kg q24h for enterolith prevention | PO |
Vitamin B complex | 20-30 ml q24h | PO |
Vitamin C | See Ascorbic acid | |
Vitamin E | 1500-2000 IU q24h for equine degenerative myeloencephalopathy prophylaxis | PO |
6000-9000 IU q24h for treatment of equine degenerative myeloencephalopathy | PO | |
Vitamin K1 | 0.5-1 mg/kg q4-6h for warfarin toxicosis | SQ |
1-2 mg/kg (divided at several sites) for sweet clover poisoning | SQ | |
0.5-2 mg/kg for foals | IM | |
Voltaren | Topical q1-6h | Ophthalmic |
Xylazine | 0.2-1.1 mg/kg | IV |
0.33-0.44 mg/kg followed by 0.033-0.066 mg/kg butorphanol | IV | |
1.1 mg/kg followed by 1.75-2.2 mg/kg ketamine | IV | |
0.6 mg/kg with 0.02 mg/kg acepromazine | IV | |
0.66 mg/kg to ejaculate ex-copula | IV | |
Yohimbine | 0.12 mg/kg for xylazine or detomidine antagonism | Slow IV |
0.075 mg/kg to restore intestinal motility | IV |
IM, intramuscular; IV, intravenous; PO, by mouth; SQ, subcutaneous; q, ery; h, hour; d, day; wk, week.
It is recommended that the manufacturer’s literature be checked before a drug is used. Many drugs have not been approved for use in horses.