Pointers

By | 2011-08-05

Dog Breed Predisposition to Conditions, Diseases and Disorders

Cardiovascular conditions

Aortic stenosis

• Congenital

• No sex predilection

• Mode of inheritance may be autosomal dominant with modifying genes or polygenic

Hypertrophic cardiomyopathy

• Rare

• Inherited in this breed

Pericardial effusion

• Acquired

• Relative risk 9.5

Dermatological conditions

Nasal folliculitis/furunculosis

• Uncommon

• Cause unknown

Muzzle folliculitis/furunculosis

• Also known as canine acne

• Local trauma, hormones and genetics may play a role in the pathogenesis

Pododermatitis

• Can affect any age or sex

• Males predisposed

• Front feet more commonly affected

Blastomycosis

• See under Infectious conditions

Coccidiomycosis

• See under Infectious conditions

Histoplasmosis

• See under Infectious conditions

Discoid lupus erythematosus

• No age or sex predisposition

• Accounted for 0.3% of skin diseases at one referral institution

Hereditary lupoid dermatosis of German Short-haired Pointers

• Familial

• Cause unknown

• Age of onset 6 months

Black hair follicular dysplasia

• Rare

• Early onset

• Familial

Acral mutilation syndrome

• Probably inherited as an autosomal recessive trait

• No sex predisposition

• Age of onset: 3-5 months

Nasal depigmentation

• Also known as Dudley nose

• Cause unknown

Truncal solar dermatitis

• Sunnier climates predispose

Zinc-responsive dermatosis

• Occurs in rapidly-growing dogs fed zinc-deficient diets

Skin tumours

• See under Neoplastic conditions

Endocrine conditions

Central diabetes insipidus (CDI) (German Short-haired Pointers)

• One report of CDI diagnosed in a litter of five 8-week-old pups suggesting a possible familial basis

Gastrointestinal conditions

Cleft palate

• Congenital disorder with inheritance suspected in this breed

Oropharyngeal neoplasia (German Short-haired Pointers)

• Possible breed predisposition

Haematological conditions

Von Willebrand’s disease

• Affects German Short-haired and German Wire-haired Pointers

• This breed is predisposed to type II disease

Infectious conditions

Blastomycosis

• Increased incidence in this breed possibly due to an increased likelihood of exposure

• Seen mainly in young male dogs living near water

• Geographic distribution: around the Mississippi, Ohio, Missouri, Tennessee, and St Lawrence Rivers, the southern Great Lakes and the southern mid-Atlantic states; not reported in the UK

Coccidiomycosis

• Increased incidence in this breed possibly due to an increased likelihood of exposure

• Seen mainly in young male dogs

• Geographic distribution: California, Arizona, Texas, New Mexico, Nevada, Utah, Mexico and parts of Central and South America; not reported in the UK

Histoplasmosis

• Uncommon

• Mainly restricted to the central United States

• Usually affects dogs less than 4 years old

Infectious skin diseases

• See under Dermatological conditions

Musculoskeletal conditions

Polyarthritis/meningitis

• Idiopathic

• Affects dogs from 6 months of age onwards

English Pointer enchondrodystrophy

• Short limbs

• Probably inherited as an autosomal recessive trait

Cranial cruciate ligament rupture

• Common cause of hind-limb lameness

• More common in German Short-haired Pointers

Umbilical hernia Hemivertebrae

• See under Neurological conditions

Neoplastic conditions

Mast cell tumours

• Possible breed predisposition

• May be seen at any age (from 4 months onwards), but usually seen in older animals

Cutaneous haemangioma (English Pointers)

• Possible breed predisposition

• Average age was 8.7 years in one study

Oropharyngeal neoplasia (German Short-haired Pointers)

• Possible breed predisposition

Nasal cavity tumours (German Short-haired Pointers)

• Reported to be at increased risk for nasal carcinoma

• Usually older dogs

• Dogs in urban areas may be at increased risk

Neurological conditions

Congenital deafness

• Signs seen from birth

Spinal muscular atrophy (English Pointers)

• Inheritance suspected

• Reported in Japan

• Age of clinical onset: 5 months

Sensory neuropathy (English and German Short-haired Pointers)

• Autosomal recessive inheritance

• Rare

• Signs seen at 3-6 months

Lysosomal storage disease – GM2 gangliosidosis (Japanese and German Short-haired Pointers)

• Autosomal recessive inheritance

• Rare

• Signs seen at 6-12 months

Meningitis and polyarteritis (German Short-haired Pointers)

• Has been reported

• Age of clinical onset: < 1 year

Pyogranulomatous meningoencephalomyelitis

• Reported in this breed

• Age of clinical onset: > 1 year

Hemivertebrae (of the thoracic vertebrae in German Short-haired Pointers)

• Autosomal recessive inheritance reported in some lines

• Occasionally seen

Ocular conditions

Entropion (usually lateral lower lids)

• Breed predisposition; polygenic inheritance likely

Chronic superficial keratitis (pannus) (English Pointers)

• Breed predisposition

Eversion of the cartilage of the nictitating membrane (German Short-haired Pointers)

• Breed predisposition; believed to be inherited as a recessive trait

• Usually occurs in young dogs

Corneal dystrophy (English Pointers)

• Mode of inheritance unknown

• Lipid dystrophy

• Age of onset: 6 years

Cataract (English Pointers)

• Dominant inheritance suspected

• Localisation: lens periphery

• Age of onset: 2-3 years; progression resulting in visual deficiencies may occur

Cataract (German Short-haired and German Wire-haired Pointers)

• Inheritance suspected

• Localisation: posterior subcapsular cortex

• Age of onset: 6-18 months of age; slowly progressive

Generalised progressive retinal atrophy (GPRA) (German Short-haired and English Pointers)

• Autosomal recessive inheritance suspected

• Clinically apparent at 5-6 years in English Pointers

Reproductive conditions

XX sex reversal (German Short-haired Pointers)

• Congenital condition reported in this breed

Respiratory conditions

Primary ciliary dyskinesia

• Signs usually seen early in life

• Affects English Pointers