Springer Spaniel

By | 2011-08-05

Dog Breed Predisposition to Conditions, Diseases and Disorders

Cardiovascular conditions

Patent ductus arteriosus

• Common congenital abnormality

• Relative risk 4.0

• Females predisposed

• Mode of inheritance is polygenic

Ventricular septal defect

• Marked risk in this breed (relative risk 5.0)

• No sex predilection

• Familial in this breed; inheritance suspected

Persistent atrial standstill

• Rare condition

• May be associated with scapulohumeral muscle wasting

Dermatological conditions

Acral mutilation syndrome

• Probably inherited as an autosomal recessive trait

• No sex predisposition

• Age of onset: 3-5 months

Malassezia dermatitis

• Affects adults of any age or sex

• May be seasonal

Grass awn migration

• Common in the summer months

Food hypersensitivity

• No age or sex predisposition reported

Primary seborrhoea

• Probably inherited as an autosomal recessive trait

• Signs first appear at an early age and get worse with age

Ichthyosis

• Rare

• Congenital

• Possibly inherited as an autosomal recessive trait

Psoriasiform-lichenoid dermatosis in English Springer Spaniels

• Rare

• Only affects English Springers

• Probably genetically determined

Ehler-Danlos syndrome

• Also known as cutaneous asthenia

• Inherited group of diseases

• May be inherited as an autosomal dominant trait

• Probably lethal in homozygotes

Intertrigo

• Lip fold pyoderma occurs in Spaniels

Idiopathic onychomadesis Anal sac disease

• No sex or age predisposition noted

Skin tumours

• See under Neoplastic conditions

Gastrointestinal conditions

Secondary megaoesophagus (English Springer Spaniels)

• Familial polymyopathy may predispose to megaoesophagus

Haematological/immunological conditions

Immune-mediated haemolytic anaemia

• Common disease

• Usually affects young adult and middle-aged animals

• May be more common in bitches

• May be seasonal variations

Factor XI deficiency

• Autosomal inheritance, with homozygotes symptomatic

Phosphofructokinase deficiency

• Inherited as an autosomal recessive trait

• DNA test available

Musculoskeletal conditions

Congenital myasthenia gravis

• See under Neurological conditions

Hip dysplasia

• Welsh Springers have the twelfth worst breed mean score in the BVA/KC Hip Dysplasia Scheme as of October 2001, with a breed average score of 19

• English Springers have a better mean score of 14

Neoplastic conditions

Trichoepithelioma (English Springer Spaniels)

• Possible breed predisposition

• Average age reported as 9 years

• This breed may be predisposed to multiple trichoepitheliomas

Canine cutaneous histiocytoma

• Possible breed predisposition

• More common in young dogs 1-2 years old

Haemangiopericytoma

• Occurs at a mean age of 7-10 years

Melanoma

• Breed predisposition

• Average age 8-9 years

Cutaneous haemangioma (English Springer Spaniels)

• Possible breed predisposition

• Average age was 8.7 years in one study

Anal sac adenocarcinoma (English Springer Spaniels)

• Breed predisposition suggested in one survey of 232 cases

• Average age was 10.5 years

• Some surveys suggest a predisposition for females

Neurological conditions

Hypomyelination of the central nervous system

• X-linked recessive inheritance suggested

• Signs seen at 2-4 weeks

• Males affected

Congenital myasthenia gravis

• Rare

• Autosomal recessive inheritance suspected

• Age of clinical onset: 6-8 weeks

Lysosomal storage disease-fucosidosis (English Springer Spaniels)

• Autosomal recessive inheritance

• Seen in Australia, New Zealand, the UK, North America

• Signs seen at 1-3 years

Lysosomal storage disease – GM1 gangliosidosis (English Springer Spaniels)

• Autosomal recessive inheritance

• Rare

• Signs seen at 3-6 months

Springer Spaniel rage syndrome

• Seen in young to middle-aged dogs

Ocular conditions

Entropion (usually lower lids) (English Springer Spaniels)

• Breed predisposition, polygenic inheritance likely

Combined entropion-ectropion (‘diamond eye’) (English Springer Spaniels)

• Breed predisposition; polygenic inheritance likely

Distichiasis (Welsh Springer Spaniels)

• Breed predisposition

Plasma cell infiltration of the nictitating membrane (plasmoma) (English Springer Spaniels)

• Breed predisposition

• May be associated with pannus

Keratoconjunctivitis sicca (English Springer Spaniels)

• Breed predisposition

Chronic superficial keratitis (pannus) (English Springer Spaniels)

• Breed predisposition

• Age of onset: 1-3 years

Refractory corneal ulceration (English Springer Spaniels)

• Breed predisposition

• Usually middle-aged

Congenital, sub-epithelial, geographic corneal dystrophy (English Springer Spaniels)

• Congenital condition; predisposed breed

• Occurs in young puppies (< 10 weeks); transient condition

Corneal dystrophy

• Breed predisposition

• Endothelial dystrophy with progressive corneal oedema

Primary glaucoma/goniodysgenesis (English Springer Spaniels)

• Inheritance suspected

• Schedule 3 of the BVA/KC/ISDS Eye Scheme

Primary glaucoma/goniodysgenesis (Welsh Springer Spaniels)

• Autosomal dominant inheritance has been suggested

• Age of onset: 10 weeks to 10 years; females seem predisposed

• Schedule 1 of the BVA/KC/ISDS Eye Scheme

Cataract (English Springer Spaniels)

• Inheritance suspected

• Posterior polar subcapsular cataracts occur at 1-3 years

• Nuclear cataracts occur at 5 years and older

Cataract (Welsh Springer Spaniels)

• Autosomal recessive inheritance

• Localisation: posterior cortex

• Age of onset: 8-12 weeks; rapidly progressive to blindness at 1-2 years

• Schedule 1 of the BVA/KC/ISDS Eye Scheme

Multifocal retinal dysplasia (English Springer Spaniels)

• Congenital condition, inheritance as an autosomal recessive trait suspected

• Schedule 1 of the BVA/KC/ISDS Eye Scheme

Geographic retinal dysplasia (English Springer Spaniels)

• Congenital condition; inheritance suspected

• Reported in the UK

Total retinal dysplasia (English Springer Spaniels)

• Congenital condition; inheritance suspected

• Reported in the UK

Generalised progressive retinal atrophy (GPRA) (English Springer Spaniels)

• Autosomal recessive inheritance

• Clinically apparent within the first 2 years, progressing to blindness at 3-5 years

• A second form is clinically apparent at 7 years and progresses more slowly

• Schedule 1 BVA/KC/ISDS Eye Scheme

Generalised progressive retinal atrophy (GPRA) (Welsh Springer Spaniels)

• Autosomal recessive inheritance suspected

• Clinical onset at 5-7 years

Central progressive retinal atrophy (CPRA) or retinal pigment epithelial dystrophy (RPED) (English Springer Spaniels)

• Breed predisposition; inheritance suspected

• Schedule 1 of the BVA/KC/ISDS Eye Scheme

Microphthalmia (with multiple ocular defects) (English Springer Spaniels)

• Recessive inheritance suggested

Renal and urinary conditions

Sphincter mechanism incompetence

• Suggested breed predisposition in female dogs

Calcium phosphate urolithiasis (hydroxyapatite and carbonate apatite)

• Higher incidence has been noted in this breed in some surveys

• Average age at diagnosis is 7-11 years

Reproductive conditions

Vaginal hyperplasia

• Possible breed predisposition

Azoospermia with spermatogenic arrest (Welsh Springer Spaniels)

• Reported in this breed

Respiratory conditions

Primary ciliary dyskinesia

• Inherited defect

• Usually signs seen within first few weeks of life