Tag Archives: Acepromazine

Arterial thromboembolism in the cat

Cats with any form of cardiomyopathy have a predilection to form intracardiac thrombi in the left atrium; the incidence is highest in cats with hypertrophic cardiomyopathy. These thrombi often become lodged at the bifurcation of the iliac arteries; less frequently they may occlude the brachia!, coeliac or renal arteries. Pathophysiology Altered blood flow and vascular… Read More »

Diseases of the Throat: Diagnosis

Diagnostic Imaging Lateral and ventrodorsal radiographic views of both the skull and cervical areas are indicated. Radiopaque foreign bodies can be identified that may be missed on laryngoscopy and pharyngoscopy (e.g. sewing needle embedded in soft tissues). Radiographs are also useful in identifying bony changes associated with chronic inflammation or neoplasia, identifying clues of unreported… Read More »

Hypertrophic Cardiomyopathy: Acute Therapy

Just as with dilated cardiomyopathy, cats that have respiratory distress suspected of having heart failure secondary to hypertrophic cardiomyopathy may need to be placed in an oxygen-enriched environment as soon as possible. If possible the cat should be initially evaluated by doing a cursory physical examination, taking care not to stress the patient during this… Read More »

Treatment of Systemic Arterial Thromboembolism

Euthanasia In cats that are in acute pain that have a poor prognosis due to severe cardiomyopathy, euthanasia is a humane means of dealing with the problem. Systemic throm-boembolism is often a horrible complication of cardiomyopathy, the treatment options are all relatively poor, and rethrombosis is common. Consequently, although one should not automatically give up… Read More »

Acepromazine Maleate (PromAce, Aceproject)

Phenothiazine Sedative / Tranquilizer Highlights Of Prescribing Information • Negligible analgesic effects • Dosage may need to be reduced in debilitated or geriatric animals, those with hepatic or cardiac disease, or when combined with other agents • Inject IV slowly; do not inject into arteries • Certain dog breeds (e.g., giant breeds, sight hounds) may… Read More »

Twins

The diffuse microcotyledonary placentation of the mare makes it highly unlikely that a twin pregnancy will be carried to term. If the twin pregnancy is maintained until the latter part of gestation the placenta cannot meet the nutrient demands of the rapidly growing fetuses. Death of one or both fetuses is followed by abortion, with… Read More »

Complications Of Burns

Infection is a serious and frequent complication of burns and must be addressed at an early stage. For the most part, normal skin commensal organisms such as Streptococcus equi var. zooepidemicus, Staphylococcus aureus, and Pseudomonas aeruginosa are encountered with some complicated by other gram-negative species, such as E. coli and Clostridia spp., and yeasts can… Read More »

Atopy: Diagnostic Tests

Atopic Dermatitis Several tests can be performed if a clinician suspects a horse has atopic dermatitis. Skin biopsy shows a superficial-to-deep perivascular dermatitis with eosinophilia. This type of reaction pattern is not specific for atopy and may be seen with other types of allergies. Other diagnostic tests, including an intradermal allergy test or a serum… Read More »

Acepromazine

Acepromazine Maleate (Promace) Chemical Compound: 2-Acetyl-10-(3-dimethylaminopropyl) phenothiazine hydrogen maleate DEA Classification: Not a controlled substance Preparations: Generally available in 5-, 10-, 25-mg tablets and 10 mg/ml injectable forms Clinical Pharmacology Acepromazine is a low-potency phenothiazine neuroleptic agent that blocks postsynaptic dopamine receptors and increases the turnover rate of dopamine. Acepromazine has a depressant effect on… Read More »

Antipsychotics

Antipsychotics are used to treat most forms of psychosis, including schizophrenia, in humans. They do not have the same significance in animal behavior therapy and are usually most appropriately used on a short-term, intermittent basis. The first antipsychotic, chlorpromazine, was developed in 1950. Individual antipsychotic drugs show a wide range of physiological effects, resulting in… Read More »