Tag Archives: Acetylcysteine

Aminocaproic Acid (Amicar)

Fibrinolysis Inhibitor/Antiprotease Highlights Of Prescribing Information • May be useful for treating degenerative myelopathies in dogs; efficacy not well documented • Treatment may be very expensive, especially with large dogs • Contraindicated in DIC • Infrequently causes GI distress What Is Aminocaproic Acid Used For? Aminocaproic acid has been used as a treatment to degenerative… Read More »

Acetylcysteine (N-acetylcysteine, Mucomyst, NAC)

Antidote; Mucolytic Highlights Of Prescribing Information • Used primarily as a treatment for acetaminophen or phenol toxicity & for its mucolytic effect; used anecdotally for treating degenerative myelopathy • Also used as a topical ophthalmic () • Has caused hypersensitivity & bronchospasm when used in pulmonary tree • Administer via gastric- or duodenal tube for… Read More »

Acetaminophen (Tylenol, APAP, Paracetamol)

Oral Analgesic, Antipyretic Highlights Of Prescribing Information • Contraindicated in cats at any dosage; ferrets may be as sensitive to acetaminophen as cats • At recommended dosages, not overly toxic to dogs, rodents, or rabbits • Often used in combined dosage forms with codeine; see codeine monograph for more information What Is Acetaminophen Used For?… Read More »

Heaves (Recurrent Airway Obstruction)

Practical Management of Acute Episodes and Prevention of Exacerbations Heaves, also known as recurrent airway obstruction (RAO) and chronic obstructive pulmonary disease (COPD), is an inflammatory condition in horses that results from the inhalation of dust in moldy hay and bedding. The condition affects primarily the small airways of horses and causes bronchospasm, bronchial hyperresponsiveness,… Read More »

Guttural Pouch Empyema

Horses with empyema (pus in a body cavity) of the guttural pouch(es) are most often presented because of purulent nasal discharge. The guttural pouches open into the nasopharynx caudal to the point at which the nasal passages are completely divided by the nasal septum. This structure causes the discharge to be bilateral even if only… Read More »

Extravasation of Hemotherapeutic Drugs

1. What chemotherapy agents may cause a perivascular reaction or slough and is this truly an oncologic emergency? Many chemotherapeutic agents are known to induce significant tissue injury after extravasation. Some are severe, irreversible vesicants; others are irritants. Immediate treatment of this condition can result in reduction of dramatic morbidity and in some cases, mortality.… Read More »

Drugs used in keratoconjunctivitis sicca

Keratoconjunctivitis sicca (KCS) occurs in dogs but is rare in other species. Treatment consists of the replacement of tear secretions, or the improvement of tear secretion. Management of the condition by surgical procedures may be necessary. Ciclosporin has been shown to be effective in the treatment of some cases of keratoconjunctivitis sicca. Ciclosporin appears to… Read More »

Degenerative myelopathy

Definition and cause Degenerative myelopathy is a slow, progressive degeneration of the spinal cord, which often leads to loss of motor control of the hind legs. While no proven cause is known, it is believed that an autoaggressive process may be involved with the observed degeneration of the spinal cord. Although it is most commonly… Read More »

ACETYLCYSTEINE

Chemistry The N-acetyl derivative of L-cysteine, acetylcysteine occurs as a white, crystalline powder with a slight acetic odor. It is freely soluble in water or alcohol. Acetylcysteine may also be known as N-acetylcysteine or N-Acetyl-L-cysteine. Storage – Stability – Compatibility When unopened, vials of sodium acetylcysteine should be stored at room temperature (15-30°C). After opening,… Read More »