Tag Archives: Albuterol

Albuterol Sulfate (Salbutamol, Proventil, Ventolin)

Beta-Adrenergic Agonist Highlights Of Prescribing Information • Used primarily as a bronchodilator after PO or inhaled dosing • Use with caution in patients with cardiac dysrhythmias or dysfunction, seizure disorders, hypertension or hyperthyroidism • May be teratogenic (high doses) or delay labor What Is Albuterol Sulfate Used For? Albuterol is used principally in dogs and… Read More »

Management of Chronic Mitral Valve Insufficiency

Ideally, therapy of chronic mitral valve insufficiency would halt the progression of the valvular degeneration. Improvement of valvular function by surgical repair or valve replacement would likewise stop further deterioration. However, no therapy is currently known to inhibit or prevent the valvular degeneration, and surgery is usually not technically, economically, or ethically possible in canine… Read More »

Use of Aerosolized Bronchodilators and Corticosteroids

In recent years, aerosolized drug therapy in the horse has transitioned from a curiosity to a well established treatment modality. Practitioners and owners alike have recognized the benefit of topical application of bronchodilator and glucocorticoid drugs, thus avoiding the side effects and even toxicities associated with the systemic delivery of these drugs. Although several publications… Read More »

Treatment Modalities

Aerosolized drugs can be used to provide both quick relief of respiratory difficulty and long-term treatment (Table Recommended Dosages for Aerosolized Medications in Horses). Quick relief can be provided by short-acting β2-adrenergic agonists or anticholinergic drugs. Long-term therapy is provided by use of antiinflammatory drugs and perhaps long-acting β2-adrenoceptor agonists. Table Recommended Dosages for Aerosolized… Read More »

Sample Treatment Regimens

Case 1 The typical horse with moderate recurrent airway obstruction may have 30% to 70% neutrophils in the bronchoalveolar lavage fluid, resting airway resistance that is elevated twice to three times normal, and visible signs of increased breathing effort. This horse would show a 30% to 50% reduction in airway resistance after receiving 450 meg… Read More »

Metered-Dose Inhalant Systems

Several devices have been designed for convenient administration of aerosolized drugs formulated in a metered-dose inhaler () cannister to horses with recurrent airway obstruction (). The advantages of an metered-dose inhaler system include rapid administration, consistent ex-valve dose delivery, minimal risk of pulmonary contamination with environmental microorganisms, ease of cleaning/maintaining equipment, wide availability, and no… Read More »

Interstitial Pneumonia

Interstitial pneumonia is an uncommon cause of acute or chronic disorders of the lower respiratory tract of horses. However, because of the severity of the process, recognition and definitive diagnosis of this entity are important as early as possible in its clinical course. The term interstitial pneumonia defines a number of diseases that are chronic… Read More »

Heaves (Recurrent Airway Obstruction)

Practical Management of Acute Episodes and Prevention of Exacerbations Heaves, also known as recurrent airway obstruction (RAO) and chronic obstructive pulmonary disease (COPD), is an inflammatory condition in horses that results from the inhalation of dust in moldy hay and bedding. The condition affects primarily the small airways of horses and causes bronchospasm, bronchial hyperresponsiveness,… Read More »

Bronchodilators Recommended for the Treatment of Heaves

Bronchodilators are used in heaves-affected horses to relieve the obstruction of the small airways caused by airway smooth muscle contraction (see Table Medications Recommended for the Treatment of Heaves). Bronchodilator administration should be combined with strict environmental dust control and corticosteroid administration because inflammation of the lower airways may progress despite the improvement of clinical… Read More »

Placental Hydrops

Hydrops is a rare condition in the mare, with hydroallantois occurring more commonly than hydramnios. Hydroallantois causes rapid abdominal enlargement during the last trimester of pregnancy (), and a sudden increase in the volume of allantoic fluid during a period of 10 to 14 days. The pathophysiology of hydroallantois in the mare remains unknown. Some… Read More »