Tag Archives: Aminophylline

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Treatment And Prevention of Feline Heartworm Disease

The question arises as to whether heartworm prophylaxis is warranted for cats because they are not the natural host and because the incidence is low. Necropsy studies of feline heartworm infection in the Southeast have yielded a prevalence of 2.5% to 14%, with a median of 7%. When considering the question of institution of prophylaxis,… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Management of Chronic Mitral Valve Insufficiency

Ideally, therapy of chronic mitral valve insufficiency would halt the progression of the valvular degeneration. Improvement of valvular function by surgical repair or valve replacement would likewise stop further deterioration. However, no therapy is currently known to inhibit or prevent the valvular degeneration, and surgery is usually not technically, economically, or ethically possible in canine… Read More »

Interstitial Pneumonia

Interstitial pneumonia is an uncommon cause of acute or chronic disorders of the lower respiratory tract of horses. However, because of the severity of the process, recognition and definitive diagnosis of this entity are important as early as possible in its clinical course. The term interstitial pneumonia defines a number of diseases that are chronic… Read More »

Heaves (Recurrent Airway Obstruction)

Practical Management of Acute Episodes and Prevention of Exacerbations Heaves, also known as recurrent airway obstruction (RAO) and chronic obstructive pulmonary disease (COPD), is an inflammatory condition in horses that results from the inhalation of dust in moldy hay and bedding. The condition affects primarily the small airways of horses and causes bronchospasm, bronchial hyperresponsiveness,… Read More »

Bronchodilators Recommended for the Treatment of Heaves

Bronchodilators are used in heaves-affected horses to relieve the obstruction of the small airways caused by airway smooth muscle contraction (see Table Medications Recommended for the Treatment of Heaves). Bronchodilator administration should be combined with strict environmental dust control and corticosteroid administration because inflammation of the lower airways may progress despite the improvement of clinical… Read More »

Dimenhydrinate

Chemistry An ethanolamine derivative antihistamine, dimenhydrinate contains approximately 54% diphenhydramine and 46% 8-chlorotheophylline. It occurs as an odorless, bitter and numbing-tasting, white crystalline powder with a melting range of 102°-107°C. Dimenhydrinate is slightly soluble in water and is freely soluble in propylene glycol or alcohol. The pH of the commercially available injection ranges from 6.4… Read More »

Cythioate

Chemistry Cythioate is an oral organophosphate agent. Storage – Stability – Compatibility Unless otherwise noted by the manufacturer store products in tight, light resistant containers at room temperature. Pharmacology After being distributed into body fluids, cythioate is ingested by fleas, ticks and demodectic mites. It then inhibits acetylcholinesterase thereby interfering with neuromuscular transmission. Uses –… Read More »

Codeine Phosphate

Chemistry A phenanthrene-derivative opiate agonist, codeine is available as the base and three separate salts. Codeine base is slightly soluble in water and freely soluble in alcohol. Codeine phosphate occurs as fine, white, needle-like crystals or white, crystalline powder. It is freely soluble in water. Codeine sulfate’s appearance is similar to codeine phosphate, but it… Read More »