Tag Archives: Ammonium chloride

Dilated cardiomyopathy in the cat

The aetiology of primary dilated cardiomyopathy in the cat is unknown. Recent work has indicated a close association between dietary taurine deficiency and dilated cardiomyopathy. In the cat, taurine is an essential amino acid which is required for the conjugation of bile acids. The premise that taurine deficiency is one of the causative factors in… Read More »

Ammonium Chloride (Uroeze)

Acidifying Agent Highlights Of Prescribing Information • Urinary acidifier; treatment of metabolic alkalosis • Contraindicated in patients with hepatic failure or uremia • Potential adverse effects are primarily GI distress; IV use may lead to metabolic acidosis • May increase excretion of quinidine; decrease efficacy of erythromycin or aminoglycosides in urine What Is Ammonium Chloride… Read More »

Dimenhydrinate

Chemistry An ethanolamine derivative antihistamine, dimenhydrinate contains approximately 54% diphenhydramine and 46% 8-chlorotheophylline. It occurs as an odorless, bitter and numbing-tasting, white crystalline powder with a melting range of 102°-107°C. Dimenhydrinate is slightly soluble in water and is freely soluble in propylene glycol or alcohol. The pH of the commercially available injection ranges from 6.4… Read More »

Paresis / Paralysis

Intervertebral Disc Disease — Paresis / Paralysis Definition and cause Intervertrebal (IV) disc disease is a degeneration of the intervertebral disc, which is characterized by leakage of the disc material, leading to spinal cord compression and neurological deficits. While no proven genetic link has been determined, certain breeds such as dachshunds, beagles, and corgis are… Read More »

Codeine Phosphate

Chemistry A phenanthrene-derivative opiate agonist, codeine is available as the base and three separate salts. Codeine base is slightly soluble in water and freely soluble in alcohol. Codeine phosphate occurs as fine, white, needle-like crystals or white, crystalline powder. It is freely soluble in water. Codeine sulfate’s appearance is similar to codeine phosphate, but it… Read More »

CHLORPROPAMIDE

Chemistry An oral sulfonylurea antidiabetic agent, chlorpropamide occurs as a white, crystalline powder having a slight odor. It is practically insoluble in water. Storage – Stability – Compatibility Chlorpropamide tablets should be stored in well-closed containers at room temperature. Pharmacology Sulfonylureas lower blood glucose concentrations in both diabetic and non-diabetics. The exact mechanism of action… Read More »

ALLOPURINOL

Chemistry A xanthine oxidase inhibitor, allopurinol occurs as a tasteless, fluffy white to off-white powder with a slight odor. It melts above 300° with decomposition and has an apparent pKa of 9.4. Oxypurinol (aka oxipurinol, alloxanthine), its active metabolite, has a pKa of 7.7. Allopurinol is only very slightly soluble in both water or alcohol.… Read More »