Tag Archives: Benazepril

Balanced vasodilators

Sodium nitroprusside Sodium nitroprusside is a potent arteriolar and venodilator drug with a similar mechanism of action to the organic nitrates, h has a very short duration of action and is administered by continuous intravenous infusion starting at an initial infusion rate of 1-5 μg kg-1 min-1. It reduces pulmonary and systemic vascular resistance decreasing… Read More »

Amlodipine Besylate (Norvasc)

Calcium Channel Blocker Highlights Of Prescribing Information • Calcium channel blocker used most often for treating hypertension, especially in cats • Slight negative inotrope; use with caution in patients with heart disease, hepatic dysfunction • Potentially may cause anorexia & hypotension in cats early in therapy • Hypertension may rapidly reoccur if dosages are missed… Read More »

Canine Heartworm Disease: Complications And Specific Syndromes

Asymptomatic Heartworm Infection Most dogs with heartworm infection are asymptomatic, even though many of these have heartworm disease (radiographic and pathologic lesions). Treatment is as described previously, using melarsomine in the split-dose regimen, along with a macrolide preventative. Asymptomatic dogs may, however, become symptomatic af’er adulticidal therapy due to postadulticidal thromboembolization and lung injury (as… Read More »

Management of Chronic Mitral Valve Insufficiency

Ideally, therapy of chronic mitral valve insufficiency would halt the progression of the valvular degeneration. Improvement of valvular function by surgical repair or valve replacement would likewise stop further deterioration. However, no therapy is currently known to inhibit or prevent the valvular degeneration, and surgery is usually not technically, economically, or ethically possible in canine… Read More »

Angiotensin-Converting Enzyme Inhibitors

ACE Inhibitors Despite their symptomatic benefits, diuretics should not be used as monotherapy in the management of congestive heart failure because they further activate the renin-angiotensin system. Drugs designed to inhibit angiotensin-converting enzyme block the formation of AT II, promote an increase in the circulating levels of bradykinin, and may temporarily reduce circulating aldosterone levels.… Read More »


Chemistry Benazepril HCl, an angiotensin converting enzyme inhibitor, occurs as white to off-white crystalline powder. It is soluble in water and ethanol. Benazepril does not contain a sulfhydryl group in its structure. Storage – Stability – Compatibility Benazepril (and combination products) tablets should be stored at temperatures less than 86°F (30°C) and protected from moisture.… Read More »