Tag Archives: Chlorpromazine

Amphotericin B Desoxycholate, Amphotericin B Lipid-Based (Abelcet, Fungizone)

Antifungal Highlights Of Prescribing Information • Systemic antifungal used for serious mycotic infections • Must be administered IV • Nephrotoxicity is biggest concern, particularly with the deoxycholate form; newer lipid based products are less nephrotoxic & penetrate into tissues better, but are more expensive • Renal function monitoring essential • Amphotericin B Desoxycholate, Amphotericin B… Read More »

Photosensitivity

Photodermatitis is a cutaneous reaction induced by exposure to light. Multiple normal reactions occur in the skin with ultraviolet radiation (UVR) exposure such as photodamage (sunburn). This post is devoted to photosensitivity, a disease state in which the skin has undergone a change because of a photosensitizer and is now sensitive to exposure to UVR.… Read More »

Acepromazine

Acepromazine Maleate (Promace) Chemical Compound: 2-Acetyl-10-(3-dimethylaminopropyl) phenothiazine hydrogen maleate DEA Classification: Not a controlled substance Preparations: Generally available in 5-, 10-, 25-mg tablets and 10 mg/ml injectable forms Clinical Pharmacology Acepromazine is a low-potency phenothiazine neuroleptic agent that blocks postsynaptic dopamine receptors and increases the turnover rate of dopamine. Acepromazine has a depressant effect on… Read More »

Antipsychotics

Antipsychotics are used to treat most forms of psychosis, including schizophrenia, in humans. They do not have the same significance in animal behavior therapy and are usually most appropriately used on a short-term, intermittent basis. The first antipsychotic, chlorpromazine, was developed in 1950. Individual antipsychotic drugs show a wide range of physiological effects, resulting in… Read More »

Viral Enteritides

Most viral enteritides of dogs and cats, especially the parvovirus infections, cause an acute and usually self-limiting diarrhea, although severe cases in young or immunocompromised patients may be fatal. Canine parvovirus infection is described here as the index case for viral enteritides. Canine Parvovirus Canine parvovirus type 2 (CPV-2) is a highly contagious cause of… Read More »

Ulceration

Gastric Erosion And Ulceration Gastric erosions and ulcers are associated with a number of primary gastric and non-gastric disorders (Table Association of Gastric Ulceration and Erosion with Specific Diseases). Clinical signs range in duration and severity, from acute to chronic and mild to life threatening. The pathomechanisms underlying gastric damage can be broadly attributed to… Read More »

Diazoxide, Oral

Chemistry Related structurally to the thiazide diuretics, diazoxide occurs as an odorless, white to creamy-white, crystalline powder with a melting point of about 330°. It is practically insoluble to sparingly soluble in water and slightly soluble in alcohol. Storage – Stability – Compatibility Diazoxide capsules and oral suspensions should be stored at 2-30°C and protected… Read More »

Cisplatin

Chemistry An inorganic platinum-containing antineoplastic, cisplatin occurs as white powder. One mg is soluble in 1 ml of water or normal saline. The drug is available commercially as powder for injection and as a solution for injection. The powder for injection occurs as a white, lyophilized powder that also contains mannitol, sodium chloride and HCl… Read More »

CHLOROTHIAZIDE

CHLOROTHIAZIDE SODIUM Chemistry A thiazide diuretic structurally related to the sulfonamides, chlorothiazide occurs as a white or practically white, odorless, slightly bitter-tasting, crystalline powder. It has a melting point of approximately 355° C and pKas of 6.7 and 9.5. It is very slightly soluble in water and slightly soluble in alcohol. The pH of the… Read More »