Tag Archives: Corticotropin

Vertebrate endocrine systems

In contrast to the invertebrate endocrine system, the emphasis in the vertebrate endocrine system is on classical endocrine organs with many physiological processes controlled by these organs. However, the nervous system still exerts an influence over the endocrine system since some of the peripheral endocrine organs are under the control of the anterior pituitary, which… Read More »

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Dimenhydrinate

Chemistry An ethanolamine derivative antihistamine, dimenhydrinate contains approximately 54% diphenhydramine and 46% 8-chlorotheophylline. It occurs as an odorless, bitter and numbing-tasting, white crystalline powder with a melting range of 102°-107°C. Dimenhydrinate is slightly soluble in water and is freely soluble in propylene glycol or alcohol. The pH of the commercially available injection ranges from 6.4… Read More »

Hypoadrenocorticism

1. Define hypoadrenocorticism. Hypoadrenocorticism is the lack of production of glucocorticoids and mineralocorticoids by the adrenal glands. It may be due to a pathologic process that affects either the adrenal glands directly (primary hypoadrenocorticism) or the production or release of corticotropin-releasing hormone (CRH) by the hypothalamus or adrenocorticotropic hormone (ACTH) by the pituitary (secondary hypoadrenocorticism).… Read More »

Cytarabine

Chemistry A synthetic pyrimidine nucleoside antimetabolite, cytarabine occurs as an odorless, white to off-white, crystalline powder with a pKa of 4.35. It is freely soluble in water and slightly soluble in alcohol. Cytarabine is also commonly known as ARA-C or Cytosine Arabinoside. It may also be known as 1-beta-D-Arabinofuranosylcytosine or Arabinosylcytosine. Storage – Stability –… Read More »

CHLOROTHIAZIDE

CHLOROTHIAZIDE SODIUM Chemistry A thiazide diuretic structurally related to the sulfonamides, chlorothiazide occurs as a white or practically white, odorless, slightly bitter-tasting, crystalline powder. It has a melting point of approximately 355° C and pKas of 6.7 and 9.5. It is very slightly soluble in water and slightly soluble in alcohol. The pH of the… Read More »