Tag Archives: Epinephrine

Amitriptyline HCL (Elavil)

Tricyclic Behavior Modifier; Anti-Pruritic; Neuropathic Pain Modifier Highlights Of Prescribing Information • Tricyclic “antidepressant” used primarily for behavior disorders & neuropathic pain/pruritus in small animals • May reduce seizure thresholds in epileptic animals • Sedation & anticholinergic effects most likely adverse effects • Overdoses can be very serious in both animals & humans What Is… Read More »

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Acepromazine Maleate (PromAce, Aceproject)

Phenothiazine Sedative / Tranquilizer Highlights Of Prescribing Information • Negligible analgesic effects • Dosage may need to be reduced in debilitated or geriatric animals, those with hepatic or cardiac disease, or when combined with other agents • Inject IV slowly; do not inject into arteries • Certain dog breeds (e.g., giant breeds, sight hounds) may… Read More »

Bronchoalveolar Lavage

Today the use of fiberoptic bronchoscopy is a common and standard diagnostic procedure, which allows direct observation of the upper and lower conducting airways. During passage of the endoscope through the nasopharynx, trachea, and large bronchi, the quantity of mucous secretions can be assessed readily in addition to the degree of mucosal edema and bronchospasm.… Read More »

Postanesthetic Upper Respiratory Tract Obstruction

Upper respiratory tract () obstruction can occur in horses recovering from general anesthesia after various surgical procedures. Postanesthetic upper respiratory tract obstruction most often results from nasal edema and/or congestion and is usually mild. Other causes include arytenoid chondritis, dorsal displacement of the soft palate, and bilateral arytenoid cartilage paralysis. Bilateral arytenoid cartilage paralysis is… Read More »

Natural Colloid Therapy

Whole Blood Transfusion When deciding if a whole blood transfusion is warranted, several factors should be considered — including the severity and cause of anemia, the short life-span of transfused red blood cells (red blood cell), and compatibility testing (cross-matching). A whole blood transfusion is indicated in horses with a packed cell volume (packed cell… Read More »

Urticaria

Urticaria is a very common nodular presentation. Edema in the dermis causes a rapid onset of nodules. This condition is often referred to as “feed bumps” or “protein bumps” by the layperson. The pathogenetic mechanism is that of a type I hypersensitivity most often associated with drug administration such as antibiotics, antiinflammatory agents, or vaccines.… Read More »

Symmetrel

Pharmacology Animal Studies In animals, amantadine hydrochloride caused several pharmacologic effects at relatively high doses. Signs of motor activity stimulation (increased spontaneous motor activity and antagonism of tetrabenazine- induced sedation) occurred in mice at oral doses of 35-40 mg/kg and above. A transient vasodepressor effect, cardiac arrhythmias and a weak ganglionic-blocking effect in dogs were… Read More »

Heart Failure: Treatment Strategies

Management of Acute Decompensated Congestive Heart Failure Dogs with dilated cardiomyopathy or mitral regurgitation often present with acute onset of coughing, dyspnea, restlessness, orthopnea, and weakness subsequent to the development of severe pulmonary edema and/or low cardiac output. The immediate priorities in these patients are resolution of the pulmonary edema, maintenance of adequate tissue perfusion… Read More »