Tag Archives: Hydrochlorothiazide

Management of Chronic Mitral Valve Insufficiency

Ideally, therapy of chronic mitral valve insufficiency would halt the progression of the valvular degeneration. Improvement of valvular function by surgical repair or valve replacement would likewise stop further deterioration. However, no therapy is currently known to inhibit or prevent the valvular degeneration, and surgery is usually not technically, economically, or ethically possible in canine… Read More »

Management of Refractory Congestive Heart Failure

Over rime, many patients become refractory to standard medical therapy as disease progression continues or if a concurrent systemic disease process develops that exerts detrimental effects on the cardiovascular system (e.g., hyperadrenocorticism, hypothyroidism, renal failure, systemic Hypertension, neoplasia, anemia, pneumonia, or pulmonary thromboembolism). Infrequent causes of an acute bout of decompensation include the development of… Read More »

Management of Stable Compensated Congestive Heart Failure

After stabilization of the acute crisis, during which hemodynamic support is the goal, long-term management of heart failure ensues. The goals for this stage are to combat congestion, improve exercise capacity and quality of life, blunt adverse neurohormonal sequelae, and prolong survival time. Drugs can be administered to promote pump function (positive inotropes), to alter… Read More »

Diazoxide, Oral

Chemistry Related structurally to the thiazide diuretics, diazoxide occurs as an odorless, white to creamy-white, crystalline powder with a melting point of about 330°. It is practically insoluble to sparingly soluble in water and slightly soluble in alcohol. Storage – Stability – Compatibility Diazoxide capsules and oral suspensions should be stored at 2-30°C and protected… Read More »


CHLOROTHIAZIDE SODIUM Chemistry A thiazide diuretic structurally related to the sulfonamides, chlorothiazide occurs as a white or practically white, odorless, slightly bitter-tasting, crystalline powder. It has a melting point of approximately 355° C and pKas of 6.7 and 9.5. It is very slightly soluble in water and slightly soluble in alcohol. The pH of the… Read More »


Chemistry Benazepril HCl, an angiotensin converting enzyme inhibitor, occurs as white to off-white crystalline powder. It is soluble in water and ethanol. Benazepril does not contain a sulfhydryl group in its structure. Storage – Stability – Compatibility Benazepril (and combination products) tablets should be stored at temperatures less than 86°F (30°C) and protected from moisture.… Read More »