Tag Archives: Isoproterenol

Amiodarone HCL (Cordarone, Pacerone)

Class III Antiarrhythmic Highlights Of Prescribing Information • Antidysrhythmic agent that can be used in dogs for arrhythmias associated with left ventricular dysfunction or to convert atrial fib into sinus rhythm; very limited experience warrants cautious use • May be useful in horses to convert atrial fib or V tach into sinus rhythm • Contraindicated… Read More »

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Hypertrophic Cardiomyopathy: Chronic Therapy

Many aspects of chronic therapy of hypertrophic cardiomyopathy are controversial. All therapy is palliative. Furosemide is the only drug that has a clearly beneficial effect chronically on survival in cats with hypertrophic cardiomyopathy. Pleurocentesis Many cats with hypertrophic cardiomyopathy are dyspneic because of pleural effusion that reaccumulates despite appropriate medical therapy. These cats need periodic… Read More »

Heart Failure: Treatment Strategies

Management of Acute Decompensated Congestive Heart Failure Dogs with dilated cardiomyopathy or mitral regurgitation often present with acute onset of coughing, dyspnea, restlessness, orthopnea, and weakness subsequent to the development of severe pulmonary edema and/or low cardiac output. The immediate priorities in these patients are resolution of the pulmonary edema, maintenance of adequate tissue perfusion… Read More »

Diltiazem

Diltiazem Hydrochloride Chemistry A calcium channel blocker, diltiazem HCl occurs as a white to off-white crystalline powder having a bitter taste. It is soluble in water and alcohol. Potencies may be expressed in terms of base (active moiety) and the salt. Dosages are generally expressed in terms of the salt. Diltiazem is also known as… Read More »

Extravasation of Hemotherapeutic Drugs

1. What chemotherapy agents may cause a perivascular reaction or slough and is this truly an oncologic emergency? Many chemotherapeutic agents are known to induce significant tissue injury after extravasation. Some are severe, irreversible vesicants; others are irritants. Immediate treatment of this condition can result in reduction of dramatic morbidity and in some cases, mortality.… Read More »

ATENOLOL

Chemistry A beta1 adrenergic blocking agent, atenolol occurs as a white, crystalline powder. At 37°C, 26.5 mg are soluble in 1 ml of water. The pH of the commercially available injection is adjusted to 5.5-6.5. Storage – Stability – Compatibility Tablets should be stored at room temperature and protected from heat, light and moisture. The… Read More »

AMIODARONE HCL

Chemistry An iodinated benzofuran, amiodarone is unique structurally and pharmacologically from other antiarrhythmic agents. It occurs as a white to cream colored lipophilic powder having a pKa of approximately 6.6. Amiodarone 200 mg tablets each contain approximately 75 mg of iodine. Storage – Stability – Compatibility Tablets should be stored in tight containers, at room… Read More »