Tag Archives: Lignocaine

Positive inotropic agents

An ideal positive inotropic agent should increase the force of contraction of cardiac muscle at a given degree of end-diastolic stretch without reducing efficiency of energy use, increasing the heart rate or predisposing to cardiac arrhythmias. The drug should also lack vasoconstrictor action on peripheral blood vessels. Drugs which enhance myocardial intracellular cyclic AMP concentration… Read More »

Bradycardia

Symptomatic bradycardia results from problems of impulse generation in the sinus node and / or its conduction from the atria to the ventricles. Both of these processes are influenced by the autonomic nervous system with the parasympathetic system slowing and the sympathetic system accelerating impulse generation and conduction. Non-cardiac causes of bradycardia Sinus bradycardia is… Read More »

Ventricular arrhythmias

Site shows some of the common clinical situations associated with ventricular arrhythmias. As can be seen, many cardiac and extracardiac conditions which compromise oxygen supply to cardiac muscle leading to ischaemia, or which increase sympathetic stimulation to the heart or generate factors which are toxic to the myocardium, commonly give rise to ventricular arrhythmias. If… Read More »