Tag Archives: Methionine

Peripheral Vascular Disease

Peripheral vascular disease denotes disorders of peripheral vessels including arteries, arterioles, veins, venules, and lymphatics (Box Peripheral Vascular Diseases). Vascular lesions may result from primary vascular pathology or occur secondary to conditions originating in unrelated tissues or organ systems (Box Causes of Peripheral Lymphatic Disorders). Resultant conditions may remain asymptomatic with little or no effect… Read More »

Systemic Arterial Thromboembolism

A thrombus is a blood clot. Thrombi are usually formed (to prevent hemorrhage) when a blood vessel is traumatized. They can also form spontaneously within the cardiovascular system. A systemic thrombus becomes a systemic throm-boembolus when it dislodges from the primary site where it forms in the cardiovascular system and is pushed by blood flow… Read More »

Portosystemic Shunts

1. What is a portosystemic shunt? A portosystemic shunt is an abnormal vessel that connects the portal vein to a systemic vein. The most common locations for portosystemic shunts are a patent ductus venosus or a connection between the portal vein and caudal vena cava or azygous vein. Single extraheptic shunts are most common in… Read More »

Drugs acting on FEET

Disorders of the feet are typically characterised by lameness, although sometimes other clinical signs such as swelling, inflammation, and discharge may be seen. In farm livestock, lameness is both a major economic and a welfare problem and in horses performance can be seriously impaired. Conditions affecting horses. Thrush in horses can result from poor hoof… Read More »

LEVOCARNITINE

CARNITINE L-CARNITINE Chemistry Levocarnitine (the L-isomer of carnitine) is an amino acid derivative, synthesized in vivo from methionine and lysine. It is required for energy metabolism and has a molecular weight of 161. Storage – Stability – Compatibility Levocarnitine capsules, tablets and powder should be stored in well-closed containers at room temperature. The oral solution… Read More »

ALLOPURINOL

Chemistry A xanthine oxidase inhibitor, allopurinol occurs as a tasteless, fluffy white to off-white powder with a slight odor. It melts above 300° with decomposition and has an apparent pKa of 9.4. Oxypurinol (aka oxipurinol, alloxanthine), its active metabolite, has a pKa of 7.7. Allopurinol is only very slightly soluble in both water or alcohol.… Read More »