Tag Archives: Neomycin

Diseases of the Ear: General Principles Of Management

The therapeutic plan for otitis externa requires identification of the primary disease process and perpetuating factors. Ideally management is aimed at thoroughly cleaning and drying the ear canal, removing or managing the primary factors, controlling perpetuating factors, administering appropriate topical or systemic therapy (or both), and evaluating response to therapy. Ear Cleaning Ear cleaning serves… Read More »

Diseases Of The Middle And Inner Ear

Normal Anatomy and Physiology The middle ear consists of the tympanic membrane, three cavities (epitympanic, tympanic, and ventral), and the bony ossicles (malleus, incus, and stapes). The tympanic membrane has two parts: (1) the thin pars tensa that attaches to the manubrium of the malleus and (2), above the pars tensa, the thicker, pars flaccida.… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Portosystemic Shunts

1. What is a portosystemic shunt? A portosystemic shunt is an abnormal vessel that connects the portal vein to a systemic vein. The most common locations for portosystemic shunts are a patent ductus venosus or a connection between the portal vein and caudal vena cava or azygous vein. Single extraheptic shunts are most common in… Read More »

Antibacterial preparations

Bacterial infections of the eye in animals may be caused by Staphylococcus, Streptococcus, Bacillus, Actinobacillus, Chlamydophila (Chlamydia), Moraxella, Micrococcus, or Clostridium spp. This list is not exhaustive and the bacteria involved vary between species. Ocular infections usually present as conjunctivitis, blepharitis, keratitis, keratocon-junctivitis, or uveitis. The aminoglycosides gentamicin, tobramycin and framycetin have a broad-spectrum bactericidal… Read More »


The anti-inflammatory effects of corticosteroids are based upon their ability to suppress capillary dilatation, vascular exudation, leucocyte migration, and immunosuppression regardless of the causative agent. In chronic conditions they inhibit neovascularisation and fibroblastic activity in the eye. This may be useful in preventing scarring and pigment deposition in the cornea but disadvantageous by retarding healing.… Read More »

Intramammary preparations for lactating animals

These preparations are used to treat clinical and subclinical mastitis (see notes above). Bacterial culture and sensitivity testing should be carried out on pretreatment milk samples on a regular basis so that mastitic pathogens within a herd are identified and the most suitable therapy is administered. Pretreatment samples should be refrigerated or frozen. Veterinarians should… Read More »


This group includes streptomycin, dihydrostreptomycin, neomycin, framycetin, gentamicin, paromomycin, amikacin, tobramycin, and apramycin. All are bactericidal and active against Gram-negative organisms and some Gram-positive organisms, but not streptococci. Amikacin, gentamicin, and tobramycin are active against Pseudomonas aeruginosa. Aminoglycosides are taken up into bacteria by an oxygen-dependent process and are therefore inactive against anaerobic bacteria. They… Read More »

Compound antibacterial preparations

Compound antibacterial preparations Although in principle the use of antibacterial mixtures is not recommended, in some cases two antibacterials may be used in combination for their activity against two specific and co-existing infections, for example, a mixture of a macrolide and a sulphonamide for enteric or respiratory disease in pigs. The main components of combination… Read More »