Tag Archives: Oxacillin

Amoxicillin / Clavulanate Potassium, Amoxicillin / Clavulanic Acid (Clavamox, Augmentin)

Potentiated Aminopenicillin Highlights Of Prescribing Information • Bactericidal aminopenicillin with beta-lactamase inhibitor that expands its spectrum. Not effective against Pseudomonas or Enterobacter • Most likely adverse effects are GI related, but hypersensitivity & other adverse effects rarely occur What Is Amoxicillin / Clavulanate Potassium, Amoxicillin / Clavulanic Acid Used For? Amoxicillin/potassium clavulanate tablets and oral… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Antibacterial preparations

Bacterial infections of the eye in animals may be caused by Staphylococcus, Streptococcus, Bacillus, Actinobacillus, Chlamydophila (Chlamydia), Moraxella, Micrococcus, or Clostridium spp. This list is not exhaustive and the bacteria involved vary between species. Ocular infections usually present as conjunctivitis, blepharitis, keratitis, keratocon-junctivitis, or uveitis. The aminoglycosides gentamicin, tobramycin and framycetin have a broad-spectrum bactericidal… Read More »

Preparations for non-lactating animals

Non-lactating or dry cow therapy is administered to eliminate any subclinical infection present at the end of lactation and to prevent the establishment of new infections, including summer mastitis, during the dry period. Management plays a major part in the control of mastitis during the dry period and animals should be examined frequently, preferably twice… Read More »

Intramammary preparations for lactating animals

These preparations are used to treat clinical and subclinical mastitis (see notes above). Bacterial culture and sensitivity testing should be carried out on pretreatment milk samples on a regular basis so that mastitic pathogens within a herd are identified and the most suitable therapy is administered. Pretreatment samples should be refrigerated or frozen. Veterinarians should… Read More »

Beta-lactam antibacterials

Narrow-spectrum penicillins Beta-lactamase resistant penicillins Broad-spectrum penicillins Antipseudomonal penicillins Cephalosporins This group comprises the penicillins and the cephalosporins. They are bactericidal by interfering with cell wall synthesis. Beta-lactam antibacterials are not metabolised in the body, but are rapidly excreted unchanged in the urine. Relatively insoluble depot preparations are often used to prolong action, albeit at… Read More »

Dicloxacillin Sodium

For general information on the penicillins, including adverse effects, contraindications, overdosage, drug interactions and monitoring parameters, refer to the monograph: Penicillins, General Information. Chemistry An isoxazolyl-penicillin, dicloxaciUin sodium is a semisynthetic penicillinase-resistant penicillin. It is available commercially as the monohydrate sodium salt which occurs as a white to off-white, crystalline powder that is freely soluble… Read More »

Cytarabine

Chemistry A synthetic pyrimidine nucleoside antimetabolite, cytarabine occurs as an odorless, white to off-white, crystalline powder with a pKa of 4.35. It is freely soluble in water and slightly soluble in alcohol. Cytarabine is also commonly known as ARA-C or Cytosine Arabinoside. It may also be known as 1-beta-D-Arabinofuranosylcytosine or Arabinosylcytosine. Storage – Stability –… Read More »

AMOXICILLIN-CLAVULANATE POTASSIUM

AMOXICILLIN-CLAVULANIC ACID For general information on the penicillins, including adverse effects, contraindications, overdosage, drug interactions and monitoring parameters, refer to the monograph: Penicillins, General Information. A separate monograph for amoxicillin is found earlier in this section. Refer to it for more information on amoxicillin chemistry, storage, stability, doses, etc.. Chemistry A beta-lactamase inhibitor, clavulanate potassium… Read More »