Tag Archives: Oxytetracycline

Amphotericin B Desoxycholate, Amphotericin B Lipid-Based (Abelcet, Fungizone)

Antifungal Highlights Of Prescribing Information • Systemic antifungal used for serious mycotic infections • Must be administered IV • Nephrotoxicity is biggest concern, particularly with the deoxycholate form; newer lipid based products are less nephrotoxic & penetrate into tissues better, but are more expensive • Renal function monitoring essential • Amphotericin B Desoxycholate, Amphotericin B… Read More »

Ammonium Chloride (Uroeze)

Acidifying Agent Highlights Of Prescribing Information • Urinary acidifier; treatment of metabolic alkalosis • Contraindicated in patients with hepatic failure or uremia • Potential adverse effects are primarily GI distress; IV use may lead to metabolic acidosis • May increase excretion of quinidine; decrease efficacy of erythromycin or aminoglycosides in urine What Is Ammonium Chloride… Read More »

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Acetylcysteine (N-acetylcysteine, Mucomyst, NAC)

Antidote; Mucolytic Highlights Of Prescribing Information • Used primarily as a treatment for acetaminophen or phenol toxicity & for its mucolytic effect; used anecdotally for treating degenerative myelopathy • Also used as a topical ophthalmic () • Has caused hypersensitivity & bronchospasm when used in pulmonary tree • Administer via gastric- or duodenal tube for… Read More »

Treatment of Vasculitis

Treatment of purpura hemorrhagica and similar idiopathic vasculitides consists of the following: (1) removing the antigenic stimulus; (2) suppressing the immune response; (3) reducing vessel wall inflammation; and (4) providing supportive care. Any drugs given when the clinical signs occurred should be discontinued, or, if continued medication is necessary, an alternate drug should be chosen… Read More »

Diseases That Primarily Cause Extravascular Hemolysis

Neonatal Isoerythrolysis The primary differential diagnosis for a neonatal foal observed to have evidence of anemia and intense icterus during the first week of life is neonatal isoerythrolysis (NI). Incompatible blood group antigens between the mare and stallion combined with maternal exposure to fetal erythrocytes during gestation results in maternal production of antigen specific antibodies… Read More »

Drugs Acting On The Reproductive System

Drugs used to promote gonadal function Sex hormones Prostaglandins Myometrial stimulants Myometrial relaxants Prolactin antagonists Non-hormonal abortificants Drugs for uterine infections Many drugs are used at different stages of the oestrous cycle to manage the response of the reproductive system; these are summarised in Table Drags affecting the reproductive system. Table Drags affecting the reproductive… Read More »

Dimenhydrinate

Chemistry An ethanolamine derivative antihistamine, dimenhydrinate contains approximately 54% diphenhydramine and 46% 8-chlorotheophylline. It occurs as an odorless, bitter and numbing-tasting, white crystalline powder with a melting range of 102°-107°C. Dimenhydrinate is slightly soluble in water and is freely soluble in propylene glycol or alcohol. The pH of the commercially available injection ranges from 6.4… Read More »

Small Intestinal Disease

Signs Diarrhea Diarrhea is an increase in fecal mass caused by an increase in fecal water and / or solid content. It is accompanied by an increase in frequency and / or fluidity and / or volume of feces. Yet it must be remembered that the absence of recognizable diarrhea does not preclude the possibility… Read More »