Tag Archives: Pentobarbital

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Dimenhydrinate

Chemistry An ethanolamine derivative antihistamine, dimenhydrinate contains approximately 54% diphenhydramine and 46% 8-chlorotheophylline. It occurs as an odorless, bitter and numbing-tasting, white crystalline powder with a melting range of 102°-107°C. Dimenhydrinate is slightly soluble in water and is freely soluble in propylene glycol or alcohol. The pH of the commercially available injection ranges from 6.4… Read More »

Induction of Anesthesia

General anesthesia may be induced by the use of inhalational agents or, more commonly, by the use of injectable drugs. The latter are usually administered by the intravenous route, but some will also work when given intramuscularly, e.g. ketamine. Other routes may occasionally be used (e.g. rectal, intraperitoneal, transmucosal) but, in common with all other… Read More »

Codeine Phosphate

Chemistry A phenanthrene-derivative opiate agonist, codeine is available as the base and three separate salts. Codeine base is slightly soluble in water and freely soluble in alcohol. Codeine phosphate occurs as fine, white, needle-like crystals or white, crystalline powder. It is freely soluble in water. Codeine sulfate’s appearance is similar to codeine phosphate, but it… Read More »

Anaesthesia, General

The use of general anaesthetics to produce loss of consciousness and sensation for operations on animals dates back to 1847, when several veterinary surgeons used ether. Chloroform was also used in 1847. Both have now been largely superseded by more effective anaesthetic agents. A wide choice is now available. The selection, dosage and means of… Read More »