Tag Archives: Physostigmine

Aminopentamide Hydrogen Sulfate (Centrine)

Anticholinergic/Antispasmodic Highlights Of Prescribing Information • Anticholinergic/antispasmodicfor GI indications in small animals • Typical adverse effect profile (“dry, hot, red”); potentially could cause tachycardia • Contraindicated in glaucoma; relatively contraindicated in tachycardias, heart disease, GI obstruction, etc. What Is Aminopentamide Hydrogen Sulfate Used For? The manufacturer states that the drug is indicated “in the treatment… Read More »

Amantadine HCL (Symmetrel)

Antiviral (Influenza A); Nmda Antagonist Highlights Of Prescribing Information • Antiviral drug with NMDA antagonist properties; may be useful in adjunctive therapy of chronic pain in small animals & treatment of equine influenza in horses • Very limited clinical experience; dogs may exhibit agitation & GI effects, especially early in therapy • Large interpatient variations… Read More »

Magnesium Abnormalities

1. What are the important functions of magnesium? Magnesium participates in the regulation of vascular smooth muscle tone, signal transduction, adenosine triphosphate (ATP) production, synthesis of nucleic acids, lymphocyte activation, and cytokine production. 2. Which cellular membrane-bound pumps utilize magnesium as a coenzyme? Sodium-potassium ATPase, calcium ATPase, and proton pumps. 3. How is magnesium distributed… Read More »

Cythioate

Chemistry Cythioate is an oral organophosphate agent. Storage – Stability – Compatibility Unless otherwise noted by the manufacturer store products in tight, light resistant containers at room temperature. Pharmacology After being distributed into body fluids, cythioate is ingested by fleas, ticks and demodectic mites. It then inhibits acetylcholinesterase thereby interfering with neuromuscular transmission. Uses –… Read More »

Cyproheptadine HCl

Chemistry An antihistamine that also possesses serotonin antagonist properties, cyproheptadine HCl occurs as a white to slightly yellow crystalline powder. Approximately 3.64 mg are soluble in one ml of water and 28.6 mg in one ml of alcohol. Storage – Stability – Compatibility Cyproheptadine HCl tablets and oral solution should be stored at room temperature… Read More »

Clemastine Fumarate

Chemistry Also known as meclastine fumarate or mecloprodin fumarate, clemastine fumarate is an ethanolamine antihistamine. It occurs as an odorless, faintly yellow, crystalline powder. It is very slightly soluble in water and sparingly soluble in alcohol. Tavist-D® contains clemastine fumarate in an immediate release outer shell and phenyl-propanolamine HCl in a sustained release inner matrix.… Read More »