Tag Archives: Procainamide

Ventricular arrhythmias

Site shows some of the common clinical situations associated with ventricular arrhythmias. As can be seen, many cardiac and extracardiac conditions which compromise oxygen supply to cardiac muscle leading to ischaemia, or which increase sympathetic stimulation to the heart or generate factors which are toxic to the myocardium, commonly give rise to ventricular arrhythmias. If… Read More »

Drugs used to treat ventricular arrhythmias

The drugs used most commonly in veterinary practice to treat ventricular arrhythmias are the Class I drugs (local anaesthetic agents) and the Class II drugs (beta-adrenoceptor antagonists). Site shows the ways in which these drugs interfere with the pathological mechanisms involved in arrhythmogenesis. Since the mechanisms involved in the generation of most ventricular arrhythmias cannot… Read More »

Amiodarone HCL (Cordarone, Pacerone)

Class III Antiarrhythmic Highlights Of Prescribing Information • Antidysrhythmic agent that can be used in dogs for arrhythmias associated with left ventricular dysfunction or to convert atrial fib into sinus rhythm; very limited experience warrants cautious use • May be useful in horses to convert atrial fib or V tach into sinus rhythm • Contraindicated… Read More »

Positive Inotropes

Agents capable of increasing cardiac contractility can improve a patient’s strength and exercise capacity, thereby potentially enhancing the pet’s quality of life. Ideally, these compounds would concurrently promote mortality benefits by improving cardiac efficiency and limiting the activation of endogenous compensatory mechanisms (with their detrimental long-term consequences). Unfortunately, to date most of the potent agents… Read More »

Acute Pancreatitis

1. Compare acute and chronic pancreatitis. Acute Chronic Acute inflammatory condition Long-standing inflammation No evidence of fibrosis Fibrosis and loss of acinar cell mass Mild or severe Mild or severe Reversible histopathologic changes Irreversible histopathologic changes   2. Describe the pathophysiology of severe pancreatitis. Severe pancreatitis is characterized by extensive pancreatic necrosis and multiple organ… Read More »

Gastric Dilatation And Volvulus

Gastric dilatation and gastric dilatation and volvulus are characterized by the dramatic distension of the stomach with air. With volvulus the stomach twists about its axis, moving dorsally and left of the fundus. Both dilatation and dilatation and volvulus cause caudal caval obstruction and impair venous return to the heart. This results in hypovolemic shock… Read More »


Chemistry An iodinated benzofuran, amiodarone is unique structurally and pharmacologically from other antiarrhythmic agents. It occurs as a white to cream colored lipophilic powder having a pKa of approximately 6.6. Amiodarone 200 mg tablets each contain approximately 75 mg of iodine. Storage – Stability – Compatibility Tablets should be stored in tight containers, at room… Read More »