Tag Archives: Romifidine

Bronchoalveolar Lavage

Today the use of fiberoptic bronchoscopy is a common and standard diagnostic procedure, which allows direct observation of the upper and lower conducting airways. During passage of the endoscope through the nasopharynx, trachea, and large bronchi, the quantity of mucous secretions can be assessed readily in addition to the degree of mucosal edema and bronchospasm.… Read More »

Alpha-2 Agonists

Alpha-2 adrenoceptor agonists (alpha-2 adrenergic agonists; alpha-2 agonists) These drugs are so-called because they bind to alpha-2 (α2) adrenergic receptors in the central and peripheral nervous system, and they are extremely useful agents for the veterinary anesthetist. Despite having been in use in animals since the late 1960s, there has only recently been a flurry… Read More »

How are the alpha2 agonists used clinically?

• Sedation: Although the alpha2 agonists are excellent agents for sedation in healthy patients, their profound cardiovascular effects generally contra-indicate their use in sicker animals, unless used at extremely low doses. The sedation provided by these drugs is much more predictable than that of acepromazine. The dose range for xylazine is 1-3 mg/kg intramuscular or… Read More »

Sulphonamides and potentiated sulphonamides

Sulphonamides The sulphonamides form an extensive series of drugs that differ more in their physicochemical characteristics, and hence in mode of administration and pharmacokinetics, than they do in their antibacterial activity. They act by competing with tissue factors, notably p-aminobenzoic acid, and are therefore inactive in the presence of necrotic tissue. They are bacteriostatic to… Read More »

Anaesthesia, General

The use of general anaesthetics to produce loss of consciousness and sensation for operations on animals dates back to 1847, when several veterinary surgeons used ether. Chloroform was also used in 1847. Both have now been largely superseded by more effective anaesthetic agents. A wide choice is now available. The selection, dosage and means of… Read More »