Tag Archives: Sodium bicarbonate

Amphotericin B Desoxycholate, Amphotericin B Lipid-Based (Abelcet, Fungizone)

Antifungal Highlights Of Prescribing Information • Systemic antifungal used for serious mycotic infections • Must be administered IV • Nephrotoxicity is biggest concern, particularly with the deoxycholate form; newer lipid based products are less nephrotoxic & penetrate into tissues better, but are more expensive • Renal function monitoring essential • Amphotericin B Desoxycholate, Amphotericin B… Read More »

Ammonium Chloride (Uroeze)

Acidifying Agent Highlights Of Prescribing Information • Urinary acidifier; treatment of metabolic alkalosis • Contraindicated in patients with hepatic failure or uremia • Potential adverse effects are primarily GI distress; IV use may lead to metabolic acidosis • May increase excretion of quinidine; decrease efficacy of erythromycin or aminoglycosides in urine What Is Ammonium Chloride… Read More »

Aminophylline Theophylline

Phosphodiesterase Inhibitor Bronchodilator Highlights Of Prescribing Information • Bronchodilator drug with diuretic activity; used for bronchospasm & cardiogenic pulmonary edema • Narrow therapeutic index in humans, but dogs appear to be less susceptible to toxic effects at higher plasma levels • Therapeutic drug monitoring recommended • Many drug interactions What Is Aminophylline Theophylline Used For?… Read More »

Canine Heartworm Disease: Complications And Specific Syndromes

Asymptomatic Heartworm Infection Most dogs with heartworm infection are asymptomatic, even though many of these have heartworm disease (radiographic and pathologic lesions). Treatment is as described previously, using melarsomine in the split-dose regimen, along with a macrolide preventative. Asymptomatic dogs may, however, become symptomatic af’er adulticidal therapy due to postadulticidal thromboembolization and lung injury (as… Read More »

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Allopurinol (Zyloprim)

Xanthine Oxidase Inhibitor; Purine Analog Highlights Of Prescribing Information • Used as a uric acid reducer in dogs, cats, reptiles & birds & as an alternative treatment Leishmaniasis &Trypanosomiasis in dogs • Use with caution (dosage adjustment may be required) in patients with renal or hepatic dysfunction • Contraindicated in red-tailed hawks & should be… Read More »

Treatment of Systemic Arterial Thromboembolism

Euthanasia In cats that are in acute pain that have a poor prognosis due to severe cardiomyopathy, euthanasia is a humane means of dealing with the problem. Systemic throm-boembolism is often a horrible complication of cardiomyopathy, the treatment options are all relatively poor, and rethrombosis is common. Consequently, although one should not automatically give up… Read More »

Acetylcysteine (N-acetylcysteine, Mucomyst, NAC)

Antidote; Mucolytic Highlights Of Prescribing Information • Used primarily as a treatment for acetaminophen or phenol toxicity & for its mucolytic effect; used anecdotally for treating degenerative myelopathy • Also used as a topical ophthalmic () • Has caused hypersensitivity & bronchospasm when used in pulmonary tree • Administer via gastric- or duodenal tube for… Read More »

Tetralogy of Fallot

The defining anatomic features of tetralogy of Fallot include right ventricular outflow obstruction (pulmonic stenosis), secondary right ventricular hypertrophy, a subaortic ventricular septal defect, and a rightward-positioned aorta. Pulmonic stenosis that occurs in combination with an isolated ventricular septal defect produces similar findings, but the infundibular septum is not malaligned, the aorta is normal in… Read More »