Tag Archives: Succinylcholine

Amikacin Sulfate (Amikin, Amiglyde-V)

Aminoglycoside Antibiotic Highlights Of Prescribing Information • Parenteral aminoglycoside antibiotic that has good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli • Adverse Effects: Nephrotoxicity, ototoxicity, neuromuscu-lar blockade • Cats may be more sensitive to toxic effects • Risk factors for toxicity: Preexisting renal disease, age (both neonatal & geriatric), fever, sepsis &… Read More »

Postanesthetic Upper Respiratory Tract Obstruction

Upper respiratory tract () obstruction can occur in horses recovering from general anesthesia after various surgical procedures. Postanesthetic upper respiratory tract obstruction most often results from nasal edema and/or congestion and is usually mild. Other causes include arytenoid chondritis, dorsal displacement of the soft palate, and bilateral arytenoid cartilage paralysis. Bilateral arytenoid cartilage paralysis is… Read More »

Induction of Anesthesia

Injectable agents Advantages of injectable anesthetics include ease of administration, avoiding problems related to breath-holding and prolonged induction, low cost and good availability. Disadvantages include a recovery often dependent on organ metabolism, difficulty reversing medications in emergency situations, prolonged recovery periods and necrosis of muscle cells at injection sites. Also, due to the renal portal… Read More »

Maintaining Anesthesia

Inhalational anesthesia is becoming the main method of anesthetising reptiles for prolonged procedures and as described above offers many benefits. These are enhanced still further if the reptile is intubated allowing the anesthetic to be delivered in a controlled manner. Intubation The glottis, which acts as the entrance to the trachea, is relatively rostral in… Read More »

Depolarising (non-competitive) muscle relaxants

These agents have a similar chemical structure to acetylcholine (ACh), the neurotransmitter at the neuromuscular junction. Depolarising agents bind to the postjunctional receptor and, because of their chemical similarity to acetylcholine, cause the muscle to contract initially, before it relaxes. This is seen clinically as widespread, shortlived, muscle fasciculations throughout the skeletal muscles of the… Read More »

Cythioate

Chemistry Cythioate is an oral organophosphate agent. Storage – Stability – Compatibility Unless otherwise noted by the manufacturer store products in tight, light resistant containers at room temperature. Pharmacology After being distributed into body fluids, cythioate is ingested by fleas, ticks and demodectic mites. It then inhibits acetylcholinesterase thereby interfering with neuromuscular transmission. Uses –… Read More »

Cyclophosphamide

Chemistry A nitrogen-mustard derivative, cyclophosphamide occurs as a white, crystalline powder that is soluble in water and alcohol. The commercially available injection has pH of 3 to 7.5. Cyclophosphamide may also be known as CPM, CTX or CYT. Storage – Stability – Compatibility Cyclophosphamide tablets and powder for injection should be stored at temperatures less… Read More »